Results 321 to 330 of about 137,846 (394)

Functional and structural insights into a thermostable (S)-selective amine transaminase and its improved substrate scope by protein engineering

Patti S, Rose SA, Isupov MN, Alunno IM, Riva S, Ferrandi EE, Littlechild JA, Monti D.   +7 more
europepmc   +1 more source

Hyperornithinemia-Hyperammonemia-Homocitrullinuria Syndrome in Vietnamese Patients. [PDF]

Medicina (Kaunas)
Nguyen KN, Tran VK, Nguyen NL, Can TBN, Dang TKG, Nguyen TH, Do TTM, Phuong LT, Tran TH, Ta TV, Tu NH, Vu CD.   +11 more
europepmc   +1 more source

Efficacy and safety of dotinurad versus febuxostat for the treatment of gout: a randomised, multicentre, double‐blind, phase 3 trial in China

Arthritis &Rheumatology, Accepted Article.
Objectives Dotinurad is a selective urate reabsorption inhibitor that reduces serum urate levels. We compared the efficacy and safety of dotinurad with febuxostat in Chinese patients with gout. Methods This phase 3, multicentre, randomised, double‐blind, parallel‐group study randomly allocated (1:1) eligible patients with gout to receive oral dotinurad
Jia Sun, Yu Wang, Yongjing Cheng, Dongmei Guo, Jiankang Hu, Dongzhou Liu, Zhengnan Gao, Changgui Li, Yibing Lu, Xiaodan Kong, Yu Liu, Zhenyu Jiang, Bin Yi, Hongfeng Zhang, Baijie Xu, Shihao Yu, Rieko Kokan, Kohei Ishikawa, Mikiko Kawakatsu, Zhuoli Zhang   +19 more
wiley   +1 more source

Assessment of Fasting Metabolism With Microdialysis Indicates Earlier Lipolysis in Children With VLCADD Than MCADD. [PDF]

Acta Paediatr
Olsson D, Haglind CB, Halldin M, Lajic S, Nordenström A.   +4 more
europepmc   +1 more source

Impact of Interleukin‐1 Blockade on the Development of Macrophage Activation Syndrome in Still's Disease: Incidence and Diagnostic Validity of the EULAR/ACR/PRINTO 2016 MAS Classification Criteria

Arthritis &Rheumatology, Accepted Article.
Objective To evaluate the applicability of the 2016 EULAR/ACR/PRINTO macrophage activation syndrome (MAS) classification criteria in patients with Still's disease (sJIA‐SD) treated with IL‐1‐targeted therapy and to assess the incidence of MAS in this context.
Remco G.A. Erkens, Greta Rogani, Laura Huber, Anouk Verwoerd, Dieneke Schonenberg‐Meinema, J. Merlijn van den Berg, Wineke Armbrust, G. Elizabeth Legger, Sylvia Kamphuis, Ellen J.H. Schatorjé, Esther P.A.H. Hoppenreijs, Joost F. Swart, Marc H.A. Jansen, Jorg van Loosdregt, Sebastiaan J. Vastert   +14 more
wiley   +1 more source

Transaminase and D-Amino Acid Oxidase of Trigonopsis variabilis

, 1962
S. Sentheshanmuganathan, Walter J. Nickerson   +1 more
openalex   +1 more source

Liver Transplant for Acute Cholestatic Crisis in Sickle Cell Disease. [PDF]

Transpl Int
Welland S, Kamp JC, Hartleben B, Taubert R, Abu Isneineh R.   +4 more
europepmc   +1 more source

Assessment of ethnic differences in pharmacokinetics and clinical responses of acalabrutinib between Chinese and White patients with B‐cell malignancies

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The aim of this study was to assess differences between Chinese and White patients in pharmacokinetics (PK) of, and clinical response to, acalabrutinib and its pharmacologically active major metabolite, ACP‐5862, to support recommended dosing in Chinese patients with B‐cell malignancies.
Tingting Yao, Junjie Ding, Shringi Sharma, Yunfei Li, Qianwei Xu, Peiming Ma   +5 more
wiley   +1 more source

Nonspecific Stimulation of Tyrosine-α-Ketoglutarate Transaminase Activity in Vivo

, 1962
Gerald Litwack, Thomas I. Diamondstone
openalex   +1 more source

Safety of remdesivir in the treatment of acute SARS-CoV-2 infection in pediatric patients. [PDF]

BMC Infect Dis
Player B, Huppler AR, Pan AY, Liegl M, Havens PL, Ray K, Mitchell M, Graff K.   +7 more
europepmc   +1 more source