Results 61 to 70 of about 6,579 (240)

Liver Transplantation After Combination Therapy Based on Immune Checkpoint Inhibitors: A Multicenter Retrospective Study of Safety and Efficacy

Organ Medicine, EarlyView.
This multicenter retrospective study assessed preoperative immune checkpoint inhibitor (ICI) therapy in 17 hepatocellular carcinoma patients undergoing liver transplantation. All received at least one cycle of ICI‐based combination therapy before transplant and achieved a 76.5% objective response rate.
Huanquan Chen, Tianxing Dai, Jie Gao, Chuanjiang Li, Huanwei Chen, Feiwen Deng, Nan Ma, Guoying Wang   +7 more
wiley   +1 more source

Influencing Factors of Lung Shunt Fraction in Transarterial Radioembolization Treatment

Clinical and Translational Imaging, 2023
Abstract Purpose We aimed to evaluate the influencing factors of lung shunt fraction(LSF) in patients who underwent transarterial radioembolization treatment. Methods We enrolled 105 patients who had either primary or metastatic liver disease.
Bilal Kovan, Caner Civan, Emine Goknur Isik, Duygu Has Simsek, Zeynep Gozde Ozkan, Fikret Buyukkaya, Yasemin Sanli, Bayram Demir, Serkan Kuyumcu   +8 more
openaire   +1 more source

Clinical Application of Radioembolization in Hepatic Malignancies: Protocol for a Prospective Multicenter Observational Study

JMIR Research Protocols, 2020
BackgroundRadioembolization, also known as transarterial radioembolization or selective internal radiation therapy with yttrium-90 (90Y) resin microspheres, is an established treatment modality for patients with primary and secondary liver tumors ...
Helmberger, Thomas, Arnold, Dirk, Bilbao, José I, de Jong, Niels, Maleux, Geert, Nordlund, Anders, Peynircioglu, Bora, Sangro, Bruno, Sharma, Ricky A, Walk, Agnes   +9 more
doaj   +1 more source

Hepatocellular carcinoma and multidrug resistance: Past, present and new challenges for therapy improvement [PDF]

, 2015
Hepatocellular carcinoma (HCC) is the most common malignancy of the liver and the third cause of cancer death worldwide. Chronic hepatitis due to HBV and HCV infection are two major risk factors for HCC worldwide.
Cuestas, María Luján, Mathet, Veronica Lidia, Oubiña, Jose Raul   +2 more
core   +1 more source

Characterization of long‐term survivors with liver metastases from uveal melanoma diagnosed between 2005 and 2021

International Journal of Cancer, Volume 158, Issue 8, Page 2179-2185, 15 April 2026.
What's New? Liver metastasis is an indicator of life expectancy for patients with advanced uveal melanoma (UM). Data on anticipated survival time following the diagnosis of liver metastasis, however, is lacking. The present study analyzed long‐term survival among UM patients who lived three or more years after liver metastases were diagnosed.
Jona Laukhuf, Lisa Wiens, Gerd Grözinger, Helmut Dittmann, Karolin Thiel, Ulrike Leiter, Teresa Amaral, Lena Nanz, Lukas Flatz, Markus Reitmajer, Andrea Forschner   +10 more
wiley   +1 more source

Radioembolization Is a Safe and Effective Treatment for Hepatocellular Carcinoma with Portal Vein Thrombosis: A Propensity Score Analysis.

PLoS ONE, 2016
Background/aimsLimited treatment options are available for patients with hepatocellular carcinoma (HCC) with portal vein thrombosis (PVT). Transarterial radioembolization using Yttrium-90 microspheres is a new treatment modality for HCC with PVT.
Young Youn Cho, Minjong Lee, Hyo-Cheol Kim, Jin Wook Chung, Yun Hwan Kim, Geum-Youn Gwak, Si Hyun Bae, Do Young Kim, Jeong Heo, Yoon Jun Kim   +9 more
doaj   +1 more source

Hepatic Abscess following Yttrium-90 Radioembolization in Patients with Surgical Bilioenteric Anastomosis or Compromised Sphincter of Oddi: A Tertiary Cancer Center Experience

Current Oncology, 2022
Purpose: We describe our experience with the development of hepatobiliary infection in patients with prior surgical, percutaneous, or endoscopic biliary interventions who are receiving transarterial radioembolization (TARE) with yttrium-90 (90Y) for ...
Kevin N. Agahi, Armeen Mahvash, Mohamed E. Abdelsalam   +2 more
doaj   +1 more source

Quantitative pretreatment VOI analysis of liver metastases 99mTc-MAA SPECT/CT and FDG PET/CT in relation with treatment response to SIRT [PDF]

, 2013
Using quantitive VOI analysis, the percentage Tc-99m-MAA uptake and SUVmax and mean values of liver metastases obtained prior to SIRT were related to treatment response using both a lesion-based and clinical dichotomous approach. Based on the VOI % of Tc-
Beels, L, Brugman, E, D'Asseler, Yves, De Spiegeleer, Bart, Maes, A, Mees, Gilles, Stellamans, K, Van De Wiele, Christophe   +7 more
core   +2 more sources

Transarterial Infusion of Pembrolizumab Plus TACE for Liver Metastases of Melanoma

Cancer Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background Melanoma hepatic metastases demonstrate limited responsiveness to conventional systemic immune checkpoint blockade therapy, primarily attributed to the hepatic microenvironment's immunosuppressive characteristics. To our knowledge, this is the first reported case describing selective hepatic arterial infusion of pembrolizumab ...
Shahram Akhlaghpoor, Hamidreza Rouientan
wiley   +1 more source

Radioembolization in the Treatment of Neuroendocrine Tumor Metastases to the Liver

International Journal of Hepatology, 2011
Surgical excision remains the preferred treatment for resectable hepatic metastases of neuroendocrine tumors. In cases of more disseminated hepatic disease, transarterial radioembolization with Yttrium-90- (90Y-) labeled microspheres has been ...
Martin Vyleta, Douglas Coldwell
doaj   +1 more source