Results 41 to 50 of about 519,603 (272)

Concept-directed transcendental arguments [PDF]

open access: yes, 2006
This thesis assesses a type of transcendental argument known as a 'concept- directed transcendental argument'. Transcendental arguments are arguments that attempt to specify the necessary conditions for experience or another feature of our mental life. A
Farningham, RPH
core  

Transcendental arguments against eliminativism [PDF]

open access: yes, 2003
Eliminativism was targeted by transcendental arguments from the first. Three responses to these arguments have emerged from the eliminativist literature—the heart of which is that such arguments are question-begging.
Lockie, Robert
core   +1 more source

Reception Baseline Assessment and ‘small acts’ of micro‐resistance

open access: yesBritish Educational Research Journal, EarlyView.
Abstract In September 2021, following the global COVID‐19 pandemic, the Department for Education introduced a national standardised digital Reception Baseline Assessment (RBA) for all English 4‐year‐old children. We analyse RBA and its associated Quality Monitoring Visits, as a further intensification of the new public management of early years ...
Guy Roberts‐Holmes   +2 more
wiley   +1 more source

Trends and Future Directions in Organic Chemistry for Drug Discovery

open access: yesChemistry – A European Journal, EarlyView.
Organic synthesis is being reshaped by the convergence of catalytic innovation, automation, artificial intelligence, and emerging therapeutic modalities. Late‐stage functionalization, photoredox and electrochemical methods, biocatalysis, flow chemistry, DELs, and proximity‐based drugs are examined as components of closed‐loop discovery.
Paweł Kozyra, Maciej Masłyk
wiley   +1 more source

Kant y Apel: el problema de la fundamentación trascendental de la moral

open access: yesRevista de Filosofia, 2011
This paper compares Kant’s arguments against a transcendental deduction of the moral law with Apel’s attempt to carry out a transcendental-pragmatic foundation of a “fundamental ethical norm.” Inspite of his improved conception of transcendental ...
José Luis López de Lizaga
doaj  

Site‐Specific Enzymatic Syntheses of DNA Bearing Several Modifications From RNA or DNA Templates

open access: yesChemistry – A European Journal, EarlyView.
A single‐tube protocol for enzymatic synthesis of DNA containing 1–3 site‐specific nucleobase modifications was developed based on repeated single nucleotide extension, primer extension, and exchange of template. ABSTRACT Two approaches for the enzymatic synthesis of DNA oligonucleotides (ONs) bearing multiple site‐specific modifications were explored.
Lukáš Kaiser   +2 more
wiley   +1 more source

Click Bioconjugation of Aza‐BODIPY Fluorophores to LfcinB Peptides for Improved Biocompatibility

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Click bioconjugation attaches NIR aza‐BODIPY fluorophores to LfcinB‐derived anticancer peptides via CuAAC and thiol‐maleimide chemistry. Conjugates exhibit improved predicted solubility while retaining strong NIR absorption (703–730 nm). Peptide‐aza‐BODIPY conjugates induce apoptotic morphology in HeLa cancer cells.
A. Verónica Rodríguez‐Mayor   +6 more
wiley   +1 more source

Elaborating Naturalized Critical Realism: Response to Ruth Groff, Dave Elder-Vass, Daniel Little and Petri Ylikoski

open access: yesJournal of Social Ontology, 2015
This paper is a reply to the discussions of Ruth Groff, Dave Elder-Vass, Daniel Little, and Petri Ylikoski of Tuukka Kaidesoja (2013): Naturalizing Critical Realist Social Ontology (London: Routledge).
Tuukka Kaidesoja
doaj   +2 more sources

Rorty, Williams, and Davidson: Skepticism and Metaepistemology

open access: yesHumanities, 2013
We revisit an important exchange on the problem of radical skepticism between Richard Rorty and Michael Williams. In his contribution to this exchange, Rorty defended the kind of transcendental approach to radical skepticism that is offered by Donald ...
Christopher Ranalli, Duncan Pritchard
doaj   +1 more source

A Three‐Parameter Continuum Timoshenko Beam Framework for Evaluating Higher‐Mode Effects in High‐Rise Buildings With Rotational and Translational Base Flexibility

open access: yesEarthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT Higher‐mode effects can significantly amplify seismic demands in high‐rise buildings, causing unintended damage over the building height. Engineered mechanisms are introduced at the base of these structures to mitigate higher‐mode effects. Existing continuum formulations for base‐flexible buildings commonly idealize the superstructure as a ...
Mohammad Hossein Asadi Jafari   +2 more
wiley   +1 more source

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