Results 71 to 80 of about 7,368 (191)

Real‐World Effectiveness and Cost‐Differential of Intranasal Esketamine Versus Intramuscular Ketamine

Psychiatric Research and Clinical Practice, EarlyView.
Objective This study evaluated whether intramuscular (IM) ketamine is non‐inferior to intranasal (IN) esketamine for treatment‐resistant depression (TRD) and assessed differences in safety and healthcare costs. Methods In a retrospective, observational sequential cohort at the VA San Diego, 179 Veterans with TRD received eight treatments of either IN ...
Kush V. Bhatt, Tara Austin, Danny Alam, Jason N. Compton, Em Ellerman‐Tayag, Gabrielle Awodele, Joel M. Boerth, Dimitri Periviliotis, Andrew Bismark, Michelle A. Singh, Michael J. McCarthy, James Pittman, Dhakshin Ramanathan   +12 more
wiley   +1 more source

Transcranial Magnetic Stimulation as a Translational Biomarker in Early‐Phase Anti‐Seizure Medication Development: A Randomized, Double‐Blind, Placebo‐Controlled Study in Generalized Epilepsy

Clinical Pharmacology &Therapeutics, Volume 120, Issue 3, Page 673-683, September 2026.
One‐third of epilepsy patients remain treatment‐resistant, underscoring the need for novel anti‐seizure medications (ASMs) and reliable biomarkers of central target engagement. Cortical hyperexcitability is a hallmark of epilepsy, making excitability a valuable pharmacodynamic biomarker for early‐phase drug development supporting go/no‐go decision ...
Catherine M. E. de Cuba, Titia Q. Ruijs, Annika A. de Goede, Robert J. Doll, Maria Juachon, Michel J. A. M. van Putten, Geert Jan Groeneveld, Jules A. A. C. Heuberger   +7 more
wiley   +1 more source

From regulatory mechanisms to cutting‐edge applications: Research progress of ultrasound, electrical, magnetic, and optical stimulation in neural modulation

Journal of Intelligent Medicine, Volume 3, Issue 3, Page 196-219, September 2026.
Abstract In recent years, the clinical treatment and symptom management of neurological disorders have faced significant challenges due to the high complexity of the nervous system's structure and function. Against this backdrop, physical stimulation techniques have emerged as a vital complementary approach to traditional pharmacological treatments and
Wanying Li, Liqun Chen
wiley   +1 more source

Parametric effects of transcranial alternating current stimulation on multitasking performance

Brain Stimulation, 2019
We have previously demonstrated that transcranial alternating current stimulation (tACS) can generate positive effects on multitasking performance and associated neurophysiological measures when it is applied with anti-phase theta band stimulation across bilateral prefrontal cortex (PFC) and a short (1-min) inter-session interval (ISI).
Wan-Yu Hsu, Theodore P. Zanto, Adam Gazzaley   +2 more
openaire   +2 more sources

Repetitive Transcranial Magnetic Stimulation (rTMS) for Adolescent Depression: A Systematic Review and Meta‐Analysis of Treatment Response and Suicidal Ideation Reduction

Acta Psychiatrica Scandinavica, Volume 154, Issue 3, Page 187-202, September 2026.
ABSTRACT Introduction Major depressive disorder (MDD) affects 11%–19% of adolescents globally. Early treatment is vital, but the risk of relapse is high, with 46% relapse within 5 years, which threatens a chronic course. Hence, better solutions are needed.
Lidija Rakic, Floris Tas, Miao Chen, Indira Tendolkar, Philip van Eijndhoven, Jozarni Dlabac‐de Lange, Mieke Klein Hofmeijer, Adriaan Hoogendoorn, Didi Rhebergen   +8 more
wiley   +1 more source

Transcutaneous and transcranial electrical stimulation for enhancing military performance: an update and systematic review

Frontiers in Human Neuroscience
IntroductionElectrical stimulation (ES), including transcranial electrical stimulation (tES) and transcutaneous vagus nerve stimulation (tVNS), has shown potential for cognitive enhancement in military contexts.
Onno van der Groen, Sara A. Rafique, Nick Willmot, Margaret G. Murphy, Margaret G. Murphy, Eulalia Tisnovsky, Tad T. Brunyé, Tad T. Brunyé   +7 more
doaj   +1 more source

Welfare and Felt Duration

Noûs, Volume 60, Issue 3, Page 563-575, September 2026.
ABSTRACT How should we understand the duration of a pleasant or unpleasant sensation, insofar as its duration modulates how good or bad the experience is overall? Given that we seem able to distinguish between subjective and objective duration and that how well or badly someone's life goes is naturally thought of as something to be assessed from her ...
Andreas L. Mogensen
wiley   +1 more source

Is Transcranial Alternating Current Stimulation Effective in Modulating Brain Oscillations?

PLoS ONE, 2013
Transcranial alternating current stimulation (tACS) is a promising tool for modulating brain oscillations, as well as a possible therapeutic intervention. However, the lack of conclusive evidence on whether tACS is able to effectively affect cortical activity continues to limit its application. The present study aims to address this issue by exploiting
BRIGNANI, Debora, M. Ruzzoli, P. Mauri, MINIUSSI, Carlo   +3 more
openaire   +8 more sources

Integrated Ultrasonic Platform for Bioelectronic Control through Biological Barriers Based on Metasurface

Advanced Science, Volume 13, Issue 43, 3 August 2026.
A metasurface‐enabled ultrasonic platform achieves precise multi‐focal control through biological barriers, real‐time physiology‐driven modulation, and simultaneous wireless power and data transmission. By unifying wavefront engineering, closed‐loop feedback, and acoustic communication, this work establishes key enabling technologies toward scalable ...
Chuanxin Zhang, Hanjie Xiao, Xue Jiang, Dean Ta   +3 more
wiley   +1 more source

Neuromodulation of Working Memory: Mechanisms, Targets, and Behavioral Outcomes

Neuroscience Insights
Working memory (WM) is a capacity-limited control system that maintains and updates task-relevant representations for goal-directed cognition. Because WM declines with aging and is disrupted across neuropsychiatric and neurodegenerative disorders ...
Seyed Kiarash Sadat Rafiei, Fatemeh Ghorbani, Janan Rezaei, Ana Saremi, Maryam Rafiei, Shadi Hajizamani, Mahsa Asadi Anar, Mehrab Samiei   +7 more
doaj   +1 more source