Results 251 to 260 of about 48,751 (307)

Osteoarthritis: Epidemiology, Diagnosis, and Treatment

MedComm, Volume 7, Issue 7, July 2026.
Osteoarthritis (OA) is a multifactorial degenerative joint disease and a leading cause of disability worldwide. This graphical abstract summarizes the epidemiology, diagnostic strategies, and therapeutic approaches of OA. OA development is driven by aging, metabolic dysregulation, and mechanical stress, leading to progressive joint degeneration ...
Qin Ru, Dongliang Yuan, Shide Jiang, Xiaoxuan Zhao, Xu Liu, Yusheng Li, Shuguang Liu, Yuxiang Wu   +7 more
wiley   +1 more source

Correction: TOPSS: TOlerability of transcranial direct current stimulation in Pediatric Stroke Survivors. [PDF]

Front Hum Neurosci
Fraser S, Clearman A, Abrahams M, Gillick B, Lal T, Savitz S, Yozbatiran N.   +6 more
europepmc   +1 more source

Epilepsy: Epidemiology, Molecular Pathogenesis, and Clinical Management

MedComm, Volume 7, Issue 7, July 2026.
Epilepsy is a heterogeneous and chronically evolving brain network disorder. This review integrates epidemiological burden, psychiatric comorbidities, and cyclic seizure patterns with multiscale pathogenic mechanisms, including ion‐channel dysfunction, synaptic transmission defects, neuroinflammation, metabolic and mitochondrial dysfunction, and ...
Jian Liu, Xinyan Wu, Ting Yin, Feining Huang, Manqi Kong, Yu Yang, Zinan Liu, Jiabin Yu, Tianpeng Zhang   +8 more
wiley   +1 more source

The effects of transcranial direct current stimulation on EEG power and complexity of ischemic stroke. [PDF]

Front Neurosci
Xi W, Song G, Ma Z, Liu L.
europepmc   +1 more source

Dexmedetomidine Rapidly Relieves Stress‐Induced Hyperalgesia via Presynaptic α2‐Adrenergic Inhibition at Orbitofrontal–Insular Glutamatergic Synapses

MedComm, Volume 7, Issue 7, July 2026.
This study identified a maladaptive OFC–AIC glutamatergic circuit in stress‐induced hyperalgesia induction. This critical circuit provides an α2‐AR‐dependent braking target for dexmedetomidine to alleviate excessive glutamatergic transmission and hyperalgesia. ABSTRACT Dexmedetomidine (Dex), an α2‐adrenergic receptor (α2‐AR) agonist, is widely used for
Hui Rong, Yang‐Xun Zhang, Huijie Zhu, Yinyao Li, Yunfan Hou, Yun‐Yong Xie, Lu‐Yao Li, Bei‐Bei Zhang, Shu‐Tao Xie, Wei Zhang, Qi‐Peng Zhang, Xiao‐Yang Zhang, Jing‐Ning Zhu, Xiaoping Gu, Zhengliang Ma   +14 more
wiley   +1 more source

Feasibility study of transcranial direct current stimulation (tDCS) efficacy in patients with neurogenic dysphagia: Study Protocol. [PDF]

MethodsX
Anhoque CF, da Silva BADS, Comarela LX, Raggazzi AM, da Silva Filho WG, Dias FMV, da Silva Arêas FZ.   +6 more
europepmc   +1 more source

A new in silico model to precisely design focused ultrasound brain therapies

Medical Physics, Volume 53, Issue 7, July 2026.
Abstract Background Focused ultrasound (FUS) combined with microbubbles enables transient and noninvasive blood–brain barrier (BBB) opening, facilitating targeted drug delivery. However, accurate treatment planning remains difficult due to inter‐patient anatomical variability and the common assumption in simulations that brain tissues behave like water.
Allegra Conti, Marta Grossi, Patricia Cardoso De Andrade, Andrea Duggento, Nicola Toschi   +4 more
wiley   +1 more source

Can exercise combined with transcranial direct current stimulation improve cognitive function in older adults? A systematic review and meta-analysis. [PDF]

Front Neurosci
Hu S, Yang Y, Li X.
europepmc   +1 more source

Respiration Can Trigger Cerebrovascular Reactivity: A Novel Method to Quantify Cerebrovascular Resistance Dynamics Using Real‐Time Phase‐Contrast MRI

Magnetic Resonance in Medicine, Volume 96, Issue 1, Page 83-95, July 2026.
ABSTRACT Purpose To directly quantify respiration‐driven cerebrovascular resistance dynamics (CRD) using a gas‐free MRI framework based on the internal‐to‐external artery carotid flow ratio (ratio_Q). Theory and Methods Two independent datasets (n = 10 and n = 17) were used to evaluate repeatability and to compare breathing conditions.
Pan Liu, Qiuting Wen, Kimi Owashi, Jean‐Marc Constans, Cyrille Capel, Olivier Balédent   +5 more
wiley   +1 more source

Co-Creation of a Study Protocol to Assess the Effect of Transcranial Direct Current Stimulation in the Management of Fatigue in Children and Young People With Acquired Brain Injury (Fatiguebrain-tDCS). [PDF]

Health Expect
Rathinam C, Heath G, Gupta R, Wassmer E, McElroy E, Horn H, Fernandez-Espejo D.   +6 more
europepmc   +1 more source