Results 101 to 110 of about 169 (168)

Feasibility of superimposed supine cycling and lower body negative pressure as an effective means of prolonging exercise tolerance in individuals experiencing persisting post‐concussive symptoms: Preliminary results

Experimental Physiology, EarlyView.
Abstract To examine the feasibility, utility and safety of superimposed lower body negative pressure (LBNP) and tilt during supine cycling in individuals suffering from persisting post‐concussive symptoms (PPCS). Eleven individuals aged 17–31 (6 females/5 males) participated in two randomized separate visits, 1 week apart.
Raelyn Javra, Joel S. Burma, Nathan E. Johnson, Jonathan D. Smirl   +3 more
wiley   +1 more source

Regional changes in cerebral blood flow between the upright and supine posture and over 3 days of bed rest

Experimental Physiology, EarlyView.
Abstract A reduction in cerebral blood flow (CBF) has been observed during spaceflight and bed rest. We aimed to examine the magnitude and regional heterogeneity of the decrease in CBF during bed rest compared to posture changes on Earth. Seventeen participants (age, 29 ± 9 years, 7 females) were studied in the upright and supine posture and over 3 ...
Carmen Possnig, Kyohei Marume, Gautam Babu, Sylvan L. J. E. Janssen, Christopher M. Hearon Jr, Katrin A. Dias, Satyam Sarma, Justin S. Lawley, Benjamin D. Levine   +8 more
wiley   +1 more source

Eccentric training at long muscle lengths induces greater corticospinal and spinal reflex plasticity than eccentric training at short muscle lengths

Experimental Physiology, EarlyView.
Abstract It is well‐established that resistance training generates neural adaptations. These may be greater when exercises mainly include eccentric contractions or when muscles are trained at long length. However, it remains to be clarified whether the length at which muscles are trained influences neural adaptation following eccentric training.
Julian Colard, Yohan Betus, Tristan Tallio, Baptiste Bizet, Antoine Nordez, Marc Jubeau, Thomas Cattagni   +6 more
wiley   +1 more source

Integrative cardiovascular dose–response to graded lower‐body negative pressure

Experimental Physiology, EarlyView.
ABSTRACT Lower‐body negative pressure (LBNP) has been posited as a potential spaceflight countermeasure to counteract the physiological deconditioning related to fluid shifts in microgravity. However, open questions remain regarding the magnitude of LBNP that should be applied.
Richard S. Whittle, Nathan Keller, Eric A. Hall, Safiyya Patanam, Bonnie J. Dunbar, Ana Diaz‐Artiles   +5 more
wiley   +1 more source

Changes in the cortical GABAergic inhibitory system with ageing and ageing‐related neurodegenerative diseases

The Journal of Physiology, EarlyView.
Abstract figure legend With ageing and age‐related neurodegenerative diseases, the amount of GABA and GABAergic inhibition as well as the modulation (indicated by sine wave) of GABAergic inhibition is reduced, whereas excitation is increased. In many parts of the brain, this leads to a mismatch of facilitatory (green neurons) and inhibitory (red ...
Wolfgang Taube, Benedikt Lauber
wiley   +1 more source

Neuromuscular mechanisms for the fast decline in rate of force development with muscle disuse – a narrative review

The Journal of Physiology, EarlyView.
Abstract figure legend Muscle unloading induces declines in muscle function, particularly in maximal and explosive strength. The decline in explosive strength (quantified as rate of force development, RFD) is greater than the decline in maximal strength (quantified as maximal force, Fmax).
Luca Ruggiero, Markus Gruber
wiley   +1 more source

Human brain imaging with high‐density electroencephalography: Techniques and applications

The Journal of Physiology, EarlyView.
Abstract figure legend Recent technological advances have elevated high‐density electroencephalography (hdEEG) to the status of a reliable neuroimaging tool. This technique measures scalp potentials with high temporal resolution, which permits the non‐invasive detection and analysis of neural oscillations.
Marco Marino, Dante Mantini
wiley   +1 more source

The ageing brain: Cortical overactivation – How does it evolve?

The Journal of Physiology, EarlyView.
Abstract figure legend Age‐related progression of brain activity over time. This review article proposes a developmental process in the ageing brain, from compensation to negative overcompensation to chronic maladaptive overcompensation, which leads to dedifferentiation and desegregation.
Wolfgang Taube, Benedikt Lauber
wiley   +1 more source

Paired corticospinal‐motoneuronal stimulation enhances ballistic motor learning and corticospinal plasticity in older adults

The Journal of Physiology, EarlyView.
Abstract figure legend The first part of this experimental study showed that late adulthood (adults aged 65–75 years) is associated with reduced motor performance and learning of simple vigorous finger movements. The second part of the study shows that ballistic motor learning can be improved in older adults when a practice session is preceded by a ...
Jonas Rud Bjørndal, Lasse Jespersen, Mikkel Malling Beck, Anke Ninija Karabanov, Lasse Christiansen, Jesper Lundbye‐Jensen   +5 more
wiley   +1 more source

Acute ketone monoester ingestion lowers resting cerebral blood flow: a randomized cross‐over trial

The Journal of Physiology, EarlyView.
Abstract figure legend This double‐blind, placebo‐controlled, randomized cross‐over trial investigated the effects of ketone monoester (KME) ingestion on resting cerebral blood flow (CBF) in young adults. We demonstrate that KME supplementation lowers CBF in a dose‐dependent manner over 2‐houra post‐ingestion, whereas CBF remained unchanged following ...
Aedan J. Rourke, Claudia M.S. Yong, Geoff B. Coombs, Addriana R. Odisho, Jenna A. Nash, Jack Bone, Baraa K. Al‐Khazraji, Jeremy J. Walsh   +7 more
wiley   +1 more source