Results 81 to 90 of about 169 (168)

The Neurophysiological Effects of Cervical Transcutaneous Spinal Cord Stimulation With and Without a High Frequency Carrier in Able‐Bodied Adults

Artificial Organs, EarlyView.
The Neurophysiological Effects of Cervical tSCS With and Without a High Frequency Carrier in Healthy Adults. kHz‐tSCS presents a less efficient waveform. In FCR, spinal inhibition was observed following sham and conv‐tSCS. kHz‐tSCS appeared to prevent FCR spinal inhibition.
Frances Gawne, Sarah Massey, Lynsey Duffell   +2 more
wiley   +1 more source

Regulating the Plasticity of Hippocampal Neurons via Electroacupuncture in Depression Model Mice

Cell Proliferation, EarlyView.
This study explores the regulation of the plasticity of hippocampal neurons via electroacupuncture in corticosterone‐induced depression model mice. Electroacupuncture at the Zusanli (ST36) acupoint alleviated depression‐like symptoms and enhanced neuronal plasticity in the hippocampal CA1 region by upregulating BDNF and CaMKIIβ, highlighting its ...
Yiyang Wang, Xinyi Du, Chenxi Duan, Miaomiao Wang, Ying Zhu, Lihua Wang, Jun Hu, Yanhong Sun   +7 more
wiley   +1 more source

Repetitive Transcranial Magnetic Stimulation Induces Cognitive Recovery in Alzheimer's Disease via GABAergic Neuron Activation of the Cx3cl1‐Cx3cr1 Axis

Cell Proliferation, EarlyView.
Schematic diagram illustrating the molecular mechanisms of the Cx3cl1‐Cx3cr1 axis mediated by rTMS activation of GABAergic neurons in the process of cognitive function recovery in AD. ABSTRACT This study aimed to investigate the impact of repetitive transcranial magnetic stimulation (rTMS) on cognitive recovery in Alzheimer's disease (AD) by exploring ...
Yunxiao Kang, Jilun Liu, Yu Wang, Jiaying Wang, Jinyang Wang, Chenming Zhou, Rui Cui, Tianyun Zhang   +7 more
wiley   +1 more source

Aetiopathogenesis of infantile epileptic spasms syndrome and mechanisms of action of adrenocorticotrophin hormone/corticosteroids in children: A scoping review

Developmental Medicine &Child Neurology, EarlyView.
Why does infantile epileptic spasms syndrome (IESS) occur with a variety of underlying conditions and why does it respond to adrenocorticotrophin hormone (ACTH)/corticosteroids? Our scoping review summarizes five hypotheses from the literature: gene/epigenetic regulation, stress/HPA axis activation, neuroinflammation/immune function, altered neuronal ...
Emily A. Innes, Velda X. Han, Shrujna Patel, Michelle A. Farrar, Deepak Gill, Shekeeb S. Mohammad, Russell C. Dale   +6 more
wiley   +1 more source

Autonomic biosignals, seizure detection, and forecasting

Epilepsia, EarlyView.
Abstract Wearable devices have attracted significant attention in epilepsy research in recent years for their potential to enhance patient care through improved seizure monitoring and forecasting. This narrative review presents a detailed overview of the current clinical state of the art while addressing how devices that assess autonomic nervous system
Gadi Miron, Mustafa Halimeh, Jesper Jeppesen, Tobias Loddenkemper, Christian Meisel   +4 more
wiley   +1 more source

The cerebellum in epilepsy

Epilepsia, EarlyView.
Abstract The cerebellum, a subcortical structure, is traditionally linked to sensorimotor integration and coordination, although its role in cognition and affective behavior, as well as epilepsy, is increasingly recognized. Cerebellar dysfunction in patients with epilepsy can result from genetic disorders, antiseizure medications, seizures, and seizure‐
Christopher Elder, Rebecca Kerestes, Puneet Opal, Maria Marchese, Orrin Devinsky   +4 more
wiley   +1 more source

Widespread decoupling of spindles and slow waves in temporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Objective Memory impairment is common in people with temporal lobe epilepsy (TLE). Recent studies in healthy subjects showed a positive correlation between sleep spindles coupled to slow waves (SWs) and memory performance. We aimed to determine differences in spindle–SW coupling in TLE patients compared to healthy controls using combined high ...
Katharina Schiller, Nicolás von Ellenrieder, Daniel Mansilla, Chifaou Abdallah, Kassem Jaber, Alfonso Garcia‐Asensi, John Thomas, Erica Minato, Jean Gotman, Birgit Frauscher   +9 more
wiley   +1 more source

Transcranial Direct Current Stimulation (tDCS) and Lymphocytes

Brain Stimulation, 2014
G. Ardolino, E. Scelzo, F. Cogiamanian, P. Bonara, A. Nozza, M. Rosa, S. Garlaschi, S. Barbieri, A. Priori   +8 more
openaire   +3 more sources

Neurobehavioral therapy in functional seizures: Investigation of mechanism of action with resting‐state functional magnetic resonance imaging

Epilepsia, EarlyView.
Abstract Objective Functional seizures (FS) often disrupt the key regions integral to cognitive processing and emotional regulation (anterior insula, anterior cingulate, and temporoparietal junction). We investigated the potential neurophysiologic mechanism of action (MOA) of neurobehavioral therapy (NBT) using resting‐state functional MRI seed‐based ...
Jerzy P. Szaflarski, W. Curt LaFrance Jr., Rodolphe Nenert, Jane B. Allendorfer, Stephen Correia, Tyler E. Gaston, Adam M. Goodman, Leslie E. Grayson, Noah Philip   +8 more
wiley   +1 more source

The human photosensitive epilepsy model for clinical proof‐of‐principle trials of novel antiseizure medications: 2. Analysis of drug trials and predictive value of the model

Epilepsia, EarlyView.
Abstract Clinical development of novel antiseizure medications (ASMs) would benefit from an early proof of principle (POP) model. The photosensitivity model, which uses the photoparoxysmal electroencephalographic response (PPR) as a surrogate of seizures, is currently the only human model that allows POP trials of investigational compounds after a ...
Wolfgang Löscher, Dorothée Kasteleijn‐Nolst Trenité   +1 more
wiley   +1 more source