Results 71 to 80 of about 30,854 (267)

The Second Hit Hypothesis in Animal and Human Dystonia: The Role of Peripheral Nerve Trauma and Spinal Cord Injury

Movement Disorders, EarlyView.
The “second‐hit” hypothesis proposes that both a genetic predisposition and an environmental insult—such as peripheral nerve trauma or spinal cord injury—are required for dystonia development. This review explores how neuroinflammation and maladaptive plasticity, triggered by nerve and spinal cord injury, contribute to dystonia pathogenesis.
Lisa Harder‐Rauschenberger, Chi Wang Ip   +1 more
wiley   +1 more source

Anodal transcranial direct current stimulation (tDCS) boosts dominant brain oscillations [PDF]

Brain Stimulation, 2018
The biological mechanisms behind the observed behavioural effects of transcranial direct current stimulation (tDCS) are still unclear and have prevented further clinical applications. The widely adopted explanation is that anodal tDCS increases the excitability of stimulated areas in a polarised manner, based on early studies with animals [1] and ...
Caroline Di Bernardi Luft, Ioanna Zioga, Joydeep Bhattacharya   +2 more
openaire   +4 more sources

Common and specific effects in brain oscillations and motor symptoms of tDCS and tACS in Parkinson’s disease

Cell Reports Medicine
Summary: Parkinson’s disease (PD) leads to neurodegeneration and abnormal brain oscillations, causing motor dysfunction. Transcranial stimulation (transcranial direct current stimulation [tDCS]/transcranial alternating current stimulation [tACS]) may ...
Jiafang Liu, Ying Zhu, Biao Chen, Qiujian Meng, Panpan Hu, Xianwen Chen, Junjie Bu   +6 more
doaj   +1 more source

Finite element model predicts current density distribution for clinical applications of tDCS and tACS

Frontiers in Psychiatry, 2012
Transcranial direct current stimulation (tDCS) has been applied in numerous scientific studies over the past decade. However, the possibility to apply tDCS in therapy of neuropsychiatric disorders is still debated. While transcranial magnetic stimulation (
Toralf eNeuling, Sven eWagner, Carsten Hermann Wolters, Tino eZaehle, Tino eZaehle, Christoph S Herrmann, Christoph S Herrmann   +6 more
doaj   +1 more source

Functional Connectivity to the Cerebellum and Resting‐State Networks Predict Earlier Improvement of Dystonia Following Globus Pallidus Internus‐Deep Brain Stimulation (GPi‐DBS)

Movement Disorders, EarlyView.
Early improvement of dystonia after globus pallidus internus‐deep brain stimulation (GPi‐DBS) is associated with stimulation of the globus pallidus externus‐subthalamic nucleus (GPe‐STN) fibers and the lenticular fasciculus. Functional connectivity to the cerebellar cortex and the limbic and default mode networks predict early improvement of symptoms ...
A. Enrique Martinez‐Nunez, Vyshak Chandra, Chance R. Fleeting, Aashay Patel, Kelly D. Foote, Justin D. Hilliard, Marta San Luciano Palenzuela, Coralie de Hemptinne, Michael S. Okun, Joshua K. Wong   +9 more
wiley   +1 more source

Exploring the Prospects of Transcranial Electrical Stimulation (tES) as a Therapeutic Intervention for Post-Stroke Motor Recovery: A Narrative Review

Brain Sciences
Introduction: Stroke survivors often have motor impairments and related functional deficits. Transcranial Electrical Stimulation (tES) is a rapidly evolving field that offers a wide range of capabilities for modulating brain function, and it is safe and ...
Hao Meng, Michael Houston, Yingchun Zhang, Sheng Li   +3 more
doaj   +1 more source

Multimodal Imaging Investigation of the Dentato‐Thalamo‐Cortical Pathway in Friedreich's Ataxia

Movement Disorders, EarlyView.
Abstract Background Friedreich's ataxia (FRDA) is a spinocerebellar neurodegenerative disorder. The dentato‐thalamo‐cortical (DTC) pathway, an important cerebellar output involved in motor control, plays a crucial role in the neural mechanisms underlying ataxia symptoms in FRDA.
Yinghua Jing, Imis Dogan, Ravi Dadsena, Jennifer Faber, Jörg B. Schulz, Kathrin Reetz, Sandro Romanzetti, on behalf of the FACROSS study group, Stella A. Lischewski, Kerstin Konrad, Miguel Pishnamaz, Maximillian Praster, Thomas Clavel, Vera Jankowski, Joachim Jankowski, Oliver Pabst, Katharina Marx‐Schütt, Nikolaus Marx, Julia Möllmann, Malte Jacobsen, Juergen Dukart, Simon Eickhoff, Ralf‐Dieter Hilgers   +22 more
wiley   +1 more source

Therapeutic Use of Non-invasive Brain Stimulation in Dystonia

Frontiers in Neuroscience, 2017
Repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) are non-invasive methods for stimulating cortical neurons that have been increasingly used in the neurology realm and in the neurosciences applied to ...
Angelo Quartarone, Angelo Quartarone, Vincenzo Rizzo, Carmen Terranova, Alberto Cacciola, Demetrio Milardi, Demetrio Milardi, Alessandro Calamuneri, Gaetana Chillemi, Paolo Girlanda   +9 more
doaj   +1 more source

Concurrent conventional & high-definition transcranial direct current stimulation for treatment of schizophrenia with co-morbid obsessive-compulsive disorder: A case report

Brain Stimulation, 2021
Non-invasive brain stimulation techniques such as conventional transcranial direct current stimulation (tDCS) and high definition tDCS (HD-tDCS) are increasingly being used as add-on treatment options in schizophrenia and obsessive-compulsive disorder ...
Swarna Buddha Nayok, Harsh Pathak, Satish Suhas, Vani H. Thimmashetty, Prakrithi Shivaprakash, Ragibommanahalli M. Madhu Sudhan, Vanteemar S. Sreeraj, Janardhanan C. Narayanaswamy, Ganesan Venkatasubramanian   +8 more
doaj   +1 more source

Effect of neurostimulation on cognition and mood in refractory epilepsy. [PDF]

, 2018
Epilepsy is a common, debilitating neurological disorder characterized by recurrent seizures. Mood disorders and cognitive deficits are common comorbidities in epilepsy that, like seizures, profoundly influence quality of life and can be difficult to ...
Chan, Alvin Y, Chang, Edward F, Rao, Vikram R, Rolston, John D   +3 more
core   +1 more source