ABSTRACT Background The dorsolateral prefrontal cortex (dlPFC) has become a cornerstone of pain neuroscience, believed critically involved in processing acute and chronic pain, as well as in pain modulation. The dlPFC is thought to balance sensory perception with the cognitive appraisal of noxious stimuli.
Lewis S. Crawford +5 more
wiley +1 more source
Home use of low-intensity transcranial electrical stimulation in clinical practice: an IFCN handbook chapter. [PDF]
Ramasawmy P +9 more
europepmc +1 more source
ABSTRACT Background Determination of death by neurologic criteria (DNC) relies on clinical examination, provided no confounding conditions affect reliability. Current guidelines require patients to be free of confounders before neurologic testing but do not specify how these confounders should be assessed or managed.
Alexander Nixon +7 more
wiley +1 more source
Central and peripheral determinants of fatigue in acute hypoxia
This thesis was submitted for the degree of Docter of Philosophy and awarded by Brunel University on 24th March 2011.Fatigue is defined as an exercise-induced decrease in maximal voluntary force produced by a muscle. Fatigue may arise from central and/or
Goodall, Stuart
core
Osteoarthritis: Epidemiology, Diagnosis, and Treatment
Osteoarthritis (OA) is a multifactorial degenerative joint disease and a leading cause of disability worldwide. This graphical abstract summarizes the epidemiology, diagnostic strategies, and therapeutic approaches of OA. OA development is driven by aging, metabolic dysregulation, and mechanical stress, leading to progressive joint degeneration ...
Qin Ru +7 more
wiley +1 more source
Modeling of cerebellar transcranial electrical stimulation effects on hand tremor in Parkinson's disease. [PDF]
Rahimi S +6 more
europepmc +1 more source
Epilepsy: Epidemiology, Molecular Pathogenesis, and Clinical Management
Epilepsy is a heterogeneous and chronically evolving brain network disorder. This review integrates epidemiological burden, psychiatric comorbidities, and cyclic seizure patterns with multiscale pathogenic mechanisms, including ion‐channel dysfunction, synaptic transmission defects, neuroinflammation, metabolic and mitochondrial dysfunction, and ...
Jian Liu +8 more
wiley +1 more source
Home-based Transcranial Electrical Stimulation (tES) for the Management of Psychiatric Disorders: A Scoping Review. [PDF]
Pathak H +6 more
europepmc +1 more source
This study identified a maladaptive OFC–AIC glutamatergic circuit in stress‐induced hyperalgesia induction. This critical circuit provides an α2‐AR‐dependent braking target for dexmedetomidine to alleviate excessive glutamatergic transmission and hyperalgesia. ABSTRACT Dexmedetomidine (Dex), an α2‐adrenergic receptor (α2‐AR) agonist, is widely used for
Hui Rong +14 more
wiley +1 more source
Long-term effect of transcranial magnetic stimulation and transcranial electrical stimulation in primary progressive aphasia: study protocol for a randomised, double-blind clinical trial (RECONNECT-PLUS). [PDF]
Fernández-Romero L +11 more
europepmc +1 more source

