Results 221 to 230 of about 45,704 (285)

Towards Mechanism‐Informed Treatments for Mental Health

Journal of Neurochemistry, Volume 170, Issue 5, May 2026.
Neuropsychiatric disorders impose a major global health burden, and current treatments, which historically mostly targeted dopamine and serotonin dysfunctions, often provide only partial, symptomatic relief. This review highlights emerging evidence that additional neuromodulator systems, including acetylcholine, norepinephrine, and endocannabinoids ...
Iker Bengoetxea de Tena, Farhanah Nabilah Sallie, Arvie Rodriguez Abiero, Beatrice Rizzi, Leandro Gabriel Champarini, Elisa Corti, Gianluca Masella, Ariel L. Dunn, Luisa Bandeira Binder, Tyler J. Wenzel, Agustin I. Robles, Roberta G. Anversa, Cécilia Tremblay, Aliance Romain Fokoua, Randriely Merscher Sobreira de Lima, Mateus D'Ávila, Trang T. T. Truong, Jessica C. Pierce, Rui S. Rodrigues, Luis Dinamarca‐Villarroel, Felipe Borges Almeida, Aino‐Kaisa Piironen, Andrey F. L. Aguiar, Andrés M. Jaramillo, Lucas Santos, Anja de Lange, David J. Nutt, Andrew J. Lawrence   +27 more
wiley   +1 more source

Huntington's Disease‐like Syndrome as a Rare Presentation of CACNA1A‐Related Disorder

Movement Disorders Clinical Practice, Volume 13, Issue 5, Page 1322-1325, May 2026.
Petros Boumis, Constantin Potagas, Christos Koros, Vasilios Constantinides, Nikolaos Ragazos, Chrysoula Koniari, Stavroula Aristeidou, Chrisoula Kartanou, Emmanouela Linardaki, Nektarios Tavernarakis, Evangelos Anagnostou, Leonidas Stefanis, Socratis Papageorgiou, Georgia Karadima, Georgios Koutsis   +14 more
wiley   +1 more source

The Reward Positivity Tracks Positive Reward Prediction Errors From Feedback to Cues During Reinforcement Learning

Psychophysiology, Volume 63, Issue 5, May 2026.
ABSTRACT How does the brain learn to predict rewards? According to temporal difference (TD) learning theory, reward prediction errors (RPEs) should shift from the time of outcome delivery to earlier predictive cues as stimulus‐action‐outcome associations are learned. The reward positivity, an electrophysiological signal believed to index sensitivity of
Yifan Gao, Robert Wilson, Galit Karpov, Travis E. Baker   +3 more
wiley   +1 more source

Heat Acclimation with Blood Flow Restriction Improves Cognitive‐Motor Dual‐Task Ability and Neuromuscular Fatigue

Scandinavian Journal of Medicine &Science in Sports, Volume 36, Issue 5, May 2026.
ABSTRACT This study examined whether heat acclimation (HA), and HA with blood flow restriction (BFR) could attenuate cognition and neuromuscular function impairments in cognitive‐motor dual‐task (CMDT) during exercise‐heat stress. Twenty trained adults were randomly assigned to one of two HA protocols over six sessions (~8 days). Each session consisted
Thomas Goepp, Oliver R. Gibson, Thomas Rupp, Mark Hayes   +3 more
wiley   +1 more source

Sex‐based differences in corticospinal excitability and inhibition

Experimental Physiology, Volume 111, Issue 5, Page 2637-2644, 1 May 2026.
Abstract The purpose of this study was to perform a novel exploration of sex‐based differences in various single‐ and paired‐pulse transcranial magnetic stimulation (TMS)‐based measures of corticospinal excitability and inhibition. Thirty participants (15 females) attended one laboratory visit where responses evoked by single‐ and paired‐pulse TMS were
Alicia M. Kells, Alexandra N. Pauhl, Anita D. Christie   +2 more
wiley   +1 more source

Opsoclonus‐Myoclonus‐Ataxia Syndrome Associated with Coexisting Anti‐N‐Methyl‐D‐Aspartate Receptor and Glial Fibrillary Acidic Protein Antibodies

Movement Disorders Clinical Practice, Volume 13, Issue 5, Page 1313-1317, May 2026.
Eriko Igami, Yutaka Oji, Akihiro Yamaguchi, Shin‐ichi Ueno, Yuji Tomizawa, Taiji Tsunemi, Taku Hatano, Nobutaka Hattori   +7 more
wiley   +1 more source

Menstrual cycle effects on sex differences in motor control during dynamic balance perturbations

Experimental Physiology, Volume 111, Issue 5, Page 2665-2681, 1 May 2026.
Abstract This study investigated sex differences in neuromuscular responses during dynamic balance perturbations and isometric maximal voluntary contractions (IMVCs) by examining if menstrual cycle (MC) phase and the fluctuations in endogenous hormones influence the observation of sex differences.
Samuli Nevanperä, Ritva S. Mikkonen, Simon Walker, Jarmo M. Piirainen   +3 more
wiley   +1 more source

Posterior Reversible Encephalopathy Syndrome in a Patient with Multiple System Atrophy and Multiple Myeloma

Movement Disorders Clinical Practice, Volume 13, Issue 5, Page 1326-1330, May 2026.
Jackson Mitzner, Jenny Linnoila, Yanal Shaheen, Abby L. Olsen   +3 more
wiley   +1 more source

Fast dynamic voluntary contractions enhance corticospinal facilitation of the human diaphragm: A transcranial magnetic stimulation study

Physiological Reports, Volume 14, Issue 9, May 2026.
Abstract In limb muscles, corticospinal excitability is modulated by motor context, with greater facilitation during movement initiation and dynamic contractions than during sustained isometric activation. Whether this applies to the human diaphragm remains uncertain, given the hybrid automatic‐voluntary control and continuous activity of respiratory ...
Alexandre Demoule, Eric Verin, Capucine Morélot‐Panzini, Christian Straus, Thomas Similowski   +4 more
wiley   +1 more source

DELirium treatment with Transcranial Electrical Stimulation (DELTES): study protocol for a multicentre, randomised, double-blind, sham-controlled trial. [PDF]

BMJ Open
van der A J, Lodema Y, Ottens TH, Schutter DJLG, Emmelot-Vonk MH, de Haan W, van Dellen E, Tendolkar I, Slooter AJC.   +8 more
europepmc   +1 more source