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Advances in transcranial focused ultrasound neuromodulation for mental disorders
Progress in Neuro-Psychopharmacology and Biological PsychiatryMental disorders are a major public health concern, affecting millions worldwide. Current treatments have limitations, highlighting the need for novel, effective, and safe interventions. Transcranial focused ultrasound (tFUS), a non-invasive neuromodulation technology, has emerged as a promising tool for treating mental disorders due to its high ...
Yu, Shi, Wen, Wu
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Numerical simulation of transcranial focused ultrasound therapy
The Journal of the Acoustical Society of America, 2015Transcranial focused ultrasound therapy is becoming a viable tool for treatment of brain related disorders. The technique has been used for treatment of essential tremors and chronic neuropathic pain with good results. In addition, the technique has a broad scope of potential applications including: tumor ablation, localized drug delivery, thrombolysis,
Aki T. Pulkkinen +3 more
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Transcranial focused ultrasound as a possible treatment for major depression
Medical Hypotheses, 2015Antidepressants are currently used as initial therapies for major depressive disorder (MDD). However, despite the remarkable increase in medications validated as effective in MDD, treatments are still plagued by inadequate responses in part of MDD patients.
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Direct phase projection and transcranial focusing of ultrasound for brain therapy
IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, 2012Ultrasound can be used to noninvasively treat the human brain with hyperthermia by focusing through the skull. To obtain an accurate focus, especially at high frequencies (>500 kHz), the phase of the transmitted wave must be modified to correct the aberrations introduced by the patient's individual skull morphology.
Gianmarco F, Pinton +2 more
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Adaptive focusing for transcranial ultrasound imaging using dual arrays
The Journal of the Acoustical Society of America, 2006Ultrasonic brain imaging remains difficult and limited because of the strong aberrating effects of the skull (absorption, diffusion and refraction of ultrasounds): high resolution transcranial imaging would require adaptive focusing techniques in order to correct the defocusing effect of the skull.
F, Vignon +4 more
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Transcranial focused ultrasound: a new tool for non-invasive neuromodulation
International Review of Psychiatry, 2017Ultrasound (US) is widely known for its utility as a biomedical imaging modality. An abundance of evidence has recently accumulated showing that US is also useful for non-invasively modulating brain circuit activity. Through a series of studies discussed in this short review, it has recently become recognized that transcranial focused ultrasound can ...
Maria Fini, William J. Tyler
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Optimization of MR-ARFI for Human Transcranial Focused Ultrasound
Abstract Magnetic resonance acoustic radiation force imaging (MR-ARFI) is an exceptionally promising technique to non-invasively confirm targeting accuracy and estimate exposure of low-intensity transcranial focused ultrasound stimulation.Morteza, Mohammadjavadi +3 more
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A Self-adaptive ultrasound patch for transcranial multimodal dynamic focusing
UltrasonicsUltrasound offers a valuable potential technology solution for continuous focused stimulation in brain science due to its non-invasive, deep penetration, and precise focusing ability. However, existing wearable focused ultrasound requires a trade-off between rigid devices that cannot conform to complex surfaces and flexible probes that have difficulty ...
Siqi Ku +6 more
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Applications of Transcranial Focused Ultrasound Surgery
Acoustics Today, 2012Daniel Pajek, Kullervo Hynynen
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