Results 11 to 20 of about 456 (150)
Focused Transcranial Ultrasound for Treatment of Neurodegenerative Dementia [PDF]
Journal of Neurodegenerative Disorders, 2019 Preclinical studies support investigation of focused ultrasound for breakdown of cerebral pathologies in neurodegenerative conditions including Alzheimer's disease (AD) and Parkinson's disease (PD).A focused transcranial Doppler device with probes (2 MHz, 520 mW/cm2) affixed bilaterally was used to target the hippocampus (AD) or substantia nigra (PD ...
Nicodemus, Natalie Eleanor +13 more
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Increased anatomical specificity of neuromodulation via modulated focused ultrasound. [PDF]
PLoS ONE, 2014 Transcranial ultrasound can alter brain function transiently and nondestructively, offering a new tool to study brain function now and inform future therapies. Previous research on neuromodulation implemented pulsed low-frequency (250-700 kHz) ultrasound
Edin Mehić +5 more
doaj +1 more source
A PVDF Receiver for Ultrasound Monitoring of Transcranial Focused Ultrasound Therapy [PDF]
IEEE Transactions on Biomedical Engineering, 2010 Focused ultrasound (FUS) shows great promise for use in the area of transcranial therapy. Currently dependent on MRI for monitoring, transcranial FUS would benefit from a real-time technique to monitor acoustic emissions during therapy. A polyvinylidene fluoride receiver with an active area of 17.8 mm (2) and a film thickness of 110 mum was constructed.
Meaghan A. O'Reilly, Kullervo Hynynen
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Frontiers in Human Neuroscience, 2022 Low intensity focused ultrasound (LIFU) has been gaining traction as a non-invasive neuromodulation technology due to its superior spatial specificity relative to transcranial electrical/magnetic stimulation.
John Dell'Italia +9 more
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Safety of Clinical Ultrasound Neuromodulation
Brain Sciences, 2022 Transcranial ultrasound holds much potential as a safe, non-invasive modality for navigated neuromodulation, with low-intensity focused ultrasound (FUS) and transcranial pulse stimulation (TPS) representing the two main modalities.
Sonja Radjenovic +3 more
doaj +1 more source
Binary acoustic metasurfaces for dynamic focusing of transcranial ultrasound
Frontiers in Neuroscience, 2022 Transcranial focused ultrasound (tFUS) is a promising technique for non-invasive and spatially targeted neuromodulation and treatment of brain diseases. Acoustic lenses were designed to correct the skull-induced beam aberration, but these designs could only generate static focused ultrasound beams inside the brain.
Zhongtao Hu +5 more
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Transcranial ultrasound simulation with uncertainty estimation [PDF]
JASA Express Letters, 2023 Transcranial ultrasound simulations are increasingly used to predict in situ exposure parameters for ultrasound therapies in the brain. However, there can be considerable uncertainty in estimating the acoustic medium properties of the skull and brain ...
Antonio Stanziola +2 more
doaj +1 more source
Neuromodulation with transcranial focused ultrasound [PDF]
Neurosurgical Focus, 2018 The understanding of brain function and the capacity to treat neurological and psychiatric disorders rest on the ability to intervene in neuronal activity in specific brain circuits. Current methods of neuromodulation incur a tradeoff between spatial focus and the level of invasiveness.
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Transcranial Focused Ultrasound for Noninvasive Neuromodulation of the Visual Cortex
IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 2020 Currently, blindness cannot be cured and patients' living quality can be compromised severely. Ultrasonic (US) neuromodulation is a promising technology for the development of noninvasive cortical visual prosthesis. We investigated the feasibility of transcranial focused ultrasound (tFUS) for noninvasive stimulation of the visual cortex (VC) to develop
Gengxi, Lu +9 more
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A rapid beam simulation framework for transcranial focused ultrasound [PDF]
Scientific Reports, 2019 AbstractTranscranial focused ultrasound is a non-invasive therapeutic modality that can be used to treat essential tremor. Beams of energy are focused into a small spot in the thalamus, resulting in tissue heating and ablation. Here, we report on a rapid 3D numeric simulation framework that can be used to predict focal spot characteristics prior to the
Steven A. Leung +4 more
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