Results 71 to 80 of about 16,712 (235)

Transcranial electrical stimulation motor threshold can estimate individualized tDCS dosage from reverse-calculation electric-field modeling

Brain Stimulation, 2020
Background: Unique amongst brain stimulation tools, transcranial direct current stimulation (tDCS) currently lacks an easy or widely implemented method for individualizing dosage.
Kevin A. Caulfield, Bashar W. Badran, William H. DeVries, Philipp M. Summers, Emma Kofmehl, Xingbao Li, Jeffrey J. Borckardt, Marom Bikson, Mark S. George   +8 more
doaj   +1 more source

Controllable pulse parameter transcranial magnetic stimulator with enhanced circuit topology and pulse shaping [PDF]

Journal of Neural Engineering, 2014
This work aims at flexible and practical pulse parameter control in transcranial magnetic stimulation (TMS), which is currently very limited in commercial devices.We present a third generation controllable pulse parameter device (cTMS3) that uses a novel circuit topology with two energy-storage capacitors.
Peterchev, Angel, D'Ostilio, Kevin, Rothwell, John, Murphy, David   +3 more
openaire   +2 more sources

Proto‐Panic Modulation by Caffeine‐Proteinoid Complexes

Journal of Applied Polymer Science, EarlyView.
Caffeine–proteinoid microspheres synthesized by thermal polymerization exhibit compartmentalized drug loading with encapsulation efficiencies of 61%–82% and triphasic release kinetics. Electrochemical monitoring reveals multi‐scale oscillatory dynamics consistent with chaotic and damped harmonic behavior, while Boolean logic operations demonstrate ...
Panagiotis Mougkogiannis, Andrew Adamatzky   +1 more
wiley   +1 more source

Effect of Theta Transcranial Alternating Current Stimulation and Phase-Locked Transcranial Pulsed Current Stimulation on Learning and Cognitive Control [PDF]

Frontiers in Neuroscience, 2019
Non-invasive brain stimulation (NIBS) is emerging as a robust treatment alternative for major depressive disorder, with a potential for achieving higher remission rates by providing targeted stimulation to underlying brain networks, such as the salience network (SN).
Farrokh Mansouri, Alaa Shanbour, Alaa Shanbour, Frank Mazza, Peter Fettes, José Zariffa, José Zariffa, José Zariffa, José Zariffa, Jonathan Downar, Jonathan Downar, Jonathan Downar, Jonathan Downar   +12 more
openaire   +3 more sources

Sustained pharmacodynamic effects of S‐ketamine on cortical excitability and resting‐state brain activity: A randomized, placebo‐controlled trial

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to investigate a set of pharmacodynamic biomarkers reflecting acute, delayed and sustained central nervous system effects of S‐ketamine, used as a tool compound for rapid‐acting antidepressant activity, with the goal of informing biomarker strategies for delayed antidepressant effects.
Catherine M. K. E. de Cuba, Annika A. de Goede, Joost. C. van Mechelen, Laura G. J. M. Borghans, Liam van der Aa, Erik Olofsen, Maria J. Juachon, Robert J. Doll, Amy Gillespie, Catherine J. Harmer, Gabriël E. Jacobs, Jules A. A. C. Heuberger   +11 more
wiley   +1 more source

Neural mechanisms underlying the after-effects of repetitive paired-pulse TMS with β tACS on the human primary motor cortex

Scientific Reports
We previously reported that repetitive paired-pulse transcranial magnetic stimulation (TMS; rPPS) synchronized to the peak phase of transcranial alternating current stimulation (tACS) at the β frequency induced long-lasting after-effects on primary motor
Hisato Nakazono, Katsuya Ogata, Tsubasa Mitsutake, Akinori Takeda, Emi Yamada, Shozo Tobimatsu   +5 more
doaj   +1 more source

A novel pulse-current waveform circuit for low-energy consumption and low-noise transcranial magnetic stimulation

Frontiers in Neuroscience
IntroductionTranscranial magnetic stimulation (TMS) is widely used for the noninvasive activation of neurons in the human brain. It utilizes a pulsed magnetic field to induce electric pulses that act on the central nervous system, altering the membrane ...
Xinhua Tan, Ao Guo, Jiasheng Tian, Yingwei Li, Yingwei Li, Jian Shi   +5 more
doaj   +1 more source

Polarity-specific cortical effects of transcranial direct current stimulation in primary somatosensory cortex of healthy humans

Frontiers in Human Neuroscience, 2016
Transcranial direct current stimulation (tDCS) is a noninvasive stimulation method that has been shown to modulate the excitability of the motor and visual cortices in human subjects in a polarity dependent manner in previous studies.
Robert eRehmann, Matthias eSczesny-Kaiser, Melanie eLenz, Tomasz eGucia, Annika eSchliesing, Peter eSchwenkreis, Martin eTegenthoff, Oliver eHöffken   +7 more
doaj   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). I. Treatments in preclinical and early clinical development

Epilepsia, EarlyView.
Abstract Over the last 34 years, the Eilat Conference on New Antiepileptic Drugs and Devices has provided an interactive forum for stakeholders to discuss investigational and recently licensed treatments for seizures and epilepsy. The Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII) took place in Madrid, Spain, on May 3 ...
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Low‐intensity focused ultrasound neuromodulation for drug‐resistant epilepsy: A randomized, sham‐controlled crossover trial

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate the safety, feasibility, and efficacy of low‐intensity focused ultrasound (LIFU) as a noninvasive neuromodulation technique in patients with drug‐resistant epilepsy (DRE). Methods In this pilot, single‐blind, randomized sham‐controlled crossover trial, 12 patients with DRE underwent both LIFU and
Chien‐Chen Chou, Yen‐Cheng Shih, Yi‐Hsiu Chen, Po‐Tso Lin, Chun‐Fu Lin, Po‐Chun Chu, Hao‐Li Liu, Cheng‐Chia Lee, Hsiang‐Yu Yu   +8 more
wiley   +1 more source