Results 51 to 60 of about 16,712 (235)

Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma, Nathan Pavey, Yukiko Tsuji, Amirul Ab Ghapar, Mehdi A.J. van den Bos, Bronwen Orden, Grace Lee, Linda Mekhael, Julie Ryder, Cláudia Santos Silva, David McDonald, Fakhria Kakar, Con Yiannikas, Matthew C. Kiernan, David A. Brown, Parvathi Menon, Steve Vucic   +16 more
wiley   +1 more source

Heart Rate Variability Features as Predictors of Intermittent Theta‐Burst Stimulation Response in Posttraumatic Stress Disorder

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Background Posttraumatic stress disorder (PTSD) is associated with autonomic dysfunction as indicated by deficits in the sympathetic and parasympathetic nervous systems. These abnormalities are expressed as elevated heart rate and reduced heart rate variability (HRV), respectively.
Camila Cosmo, Antonia V. Seligowski, Emily M. Aiken, Mascha van't Wout‐Frank, Noah S. Philip   +4 more
wiley   +1 more source

Multifocal stimulation of the cerebro-cerebellar loop during the acquisition of a novel motor skill

Scientific Reports, 2021
Transcranial direct current stimulation (tDCS)-based interventions for augmenting motor learning are gaining interest in systems neuroscience and clinical research. Current approaches focus largely on monofocal motorcortical stimulation.
Maximilian J. Wessel, Chang-hyun Park, Elena Beanato, Estelle A. Cuttaz, Jan E. Timmermann, Robert Schulz, Takuya Morishita, Philipp J. Koch, Friedhelm C. Hummel   +8 more
doaj   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa   +3 more
wiley   +1 more source

Transcranial magnetic stimulation of primary motor cortex elicits an immediate transcranial evoked potential

Brain Stimulation
Background: Transcranial evoked potentials (TEPs) measured via electroencephalography (EEG) are widely used to study the cortical responses to transcranial magnetic stimulation (TMS).
Mikkel Malling Beck, Lasse Christiansen, Mads Alexander Just Madsen, Armita Faghani Jadidi, Mikkel Christoffer Vinding, Axel Thielscher, Til Ole Bergmann, Hartwig Roman Siebner, Leo Tomasevic   +8 more
doaj   +1 more source

Personalized Network‐Guided Neuromodulation Enhances Human Working Memory

Advanced Science, EarlyView.
A personalized neuromodulation framework combining individualized functional brain network targeting with real‐time neural decoding is introduced. Using concurrent TMS–fMRI, participant‐specific stimulation targets and optimal frequencies are identified. Only optimal‐frequency stimulation improves working memory across sessions.
Ahsan Khan, Hongming Li, Camille Blaine, Julie Grier, Ethan Hammett, Almaris Figueroa‐Gonzalez, Sarai Garcia, Romain Duprat, Justin Reber, Joseph Deluisi, Christos Davatzikos, Theodore D. Satterthwaite, Yong Fan, Desmond J. Oathes   +13 more
wiley   +1 more source

Neurophysiological Effects of Transcranial Pulse Stimulation in Alzheimer’s Disease: An EEG StudyNeurophysiological Effects of Transcranial Pulse Stimulation in Alzheimer’s Disease: An EEG Study

Brain Stimulation
Lars Wojtecki
doaj   +2 more sources

Paired pulse transcranial magnetic stimulation in the assessment of biceps voluntary activation in individuals with tetraplegia

Frontiers in Human Neuroscience, 2022
After spinal cord injury (SCI), motoneuron death occurs at and around the level of injury which induces changes in function and organization throughout the nervous system, including cortical changes. Muscle affected by SCI may consist of both innervated (
Thibault Roumengous, Bhushan Thakkar, Carrie L. Peterson   +2 more
doaj   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Motor pathway abnormality in multiple sclerosis [PDF]

Romanian Journal of Neurology, 2009
Background: Multiple Sclerosis (MS) is a chronic autoimmune demyelinating disease of the central nervous system. Motor symptoms represent one of the most frequent and disabling syndrome of MS. Transcranial magnetic stimulation is a technique used for the
Orest Bolbocean, Valentin Bohotin, Cristian Dinu Popescu   +2 more
doaj   +1 more source