A Possible Mechanism of DNA to DNA Transcription in Eukaryotic Cells : Endonuclease Dependent Transcript Cutout [PDF]
We previously proposed the existence of DNA to DNA transcription in eukaryotic cells, but the mechanism by which single-stranded DNA (ssDNA) transcript is produced and released from the genome remains unknown. We once speculated that the mechanism of DNA to DNA transcription might be similar to that of DNA to RNA transcription, but now we propose that ...
arxiv
ON TRANSLITERATION AND TRANSCRIPTION [PDF]
n ...
openaire +2 more sources
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Transcription of glutamine synthetase genes (glnA and glnN) from the cyanobacterium Synechocystis sp. strain PCC 6803 is differently regulated in response to nitrogen availability [PDF]
In the cyanobacterium Synechocystis sp. strain PCC 6803 we have previously reported the presence of two different proteins with glutamine synthetase activity: GSI, encoded by the glnA gene, and GSIII, encoded by the glnN gene.
Florencio Bellido, Francisco Javier+2 more
core +1 more source
Alignment of Speech to Highly Imperfect Text Transcriptions [PDF]
We introduce a novel and inexpensive approach for the temporal alignment of speech to highly imperfect transcripts from automatic speech recognition (ASR). Transcripts are generated for extended lecture and presentation videos, which in some cases feature more than 30 speakers with different accents, resulting in highly varying transcription qualities.
arxiv
Antisense transcription licenses nascent transcripts to mediate transcriptional gene silencing [PDF]
In eukaryotes, antisense transcription can regulate sense transcription by induction of epigenetic modifications. We showed previously that antisense transcription triggers Dicer-independent siRNA (disiRNA) production and disiRNA locus DNA methylation (DLDM) in Neurospora crassa.
Yunkun Dang+4 more
openaire +2 more sources
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever+1 more
wiley +1 more source
Autoregulation of the Escherichia coli melR promoter: repression involves four molecules of MelR [PDF]
The Escherichia coli MelR protein is a transcription activator that autoregulates its own promoter by repressing transcription initiation. Optimal repression requires MelR binding to a site that overlaps the melR transcription start point and to upstream
Belyaeva+41 more
core +4 more sources
Performance Improvements of Probabilistic Transcript-adapted ASR with Recurrent Neural Network and Language-specific Constraints [PDF]
Mismatched transcriptions have been proposed as a mean to acquire probabilistic transcriptions from non-native speakers of a language.Prior work has demonstrated the value of these transcriptions by successfully adapting cross-lingual ASR systems for different tar-get languages.
arxiv
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi+3 more
wiley +1 more source