Results 111 to 120 of about 3,372,915 (384)
Gene gating at nuclear pores prevents the formation of R loops [PDF]
, 2017 Transcription is an important source of genetic variability. A large amount of transcription-associated genome variation arises from the unscheduled formation of R loops.
Aguilera López, Andrés +2 more
core +1 more source
Deep Unsupervised Drum Transcription [PDF]
arXiv, 2019 We introduce DrummerNet, a drum transcription system that is trained in an unsupervised manner. DrummerNet does not require any ground-truth transcription and, with the data-scalability of deep neural networks, learns from a large unlabeled dataset. In DrummerNet, the target drum signal is first passed to a (trainable) transcriber, then reconstructed ...
arxiv
Molecular Oncology, EarlyView.Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker +14 more
wiley +1 more source
Genome-wide analysis reveals extensive functional interaction between DNA replication initiation and transcription in the genome of trypanosoma brucei [PDF]
, 2012 Identification of replication initiation sites, termed origins, is a crucial step in understanding genome transmission in any organism. Transcription of the Trypanosoma brucei genome is highly unusual, with each chromosome comprising a few discrete ...
Blow +60 more
core +2 more sources
Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Molecular Oncology, EarlyView.Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha +6 more
wiley +1 more source
Effect of natural genetic variation on enhancer selection and function. [PDF]
, 2013 The mechanisms by which genetic variation affects transcription regulation and phenotypes at the nucleotide level are incompletely understood. Here we use natural genetic variation as an in vivo mutagenesis screen to assess the genome-wide effects of ...
Allison, KA +6 more
core
Disembodiment: Reproduction, Transcription, And Trace [PDF]
, 2018 This article poses the question, what is so great about the body? Recent scholarship has emphasized the concept of an embodied cognition and reminded us of the significance of embodiment in musical performance.
Aaron Einbond +8 more
core +1 more source
Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Molecular Oncology, EarlyView.Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi +6 more
wiley +1 more source
Plant Transcription Factors @ uni-potsdam.de [PDF]
, 2007 We present the Plant Transcription Factor Database (PlnTFDB), and the putative complete set of TFs in the algae _Chlamydomonas reinhardtii_, _Ostreococcus tauri_ and the vascular plants _Oryza sativa_ and _Arabidopsis ...
Bernd Mueller-Roeber +3 more
core +2 more sources
Music transcription modelling and composition using deep learning [PDF]
arXiv, 2016 We apply deep learning methods, specifically long short-term memory (LSTM) networks, to music transcription modelling and composition. We build and train LSTM networks using approximately 23,000 music transcriptions expressed with a high-level vocabulary (ABC notation), and use them to generate new transcriptions.
arxiv