Results 111 to 120 of about 3,535,290 (383)
Performance Improvements of Probabilistic Transcript-adapted ASR with Recurrent Neural Network and Language-specific Constraints [PDF]
arXiv, 2016 Mismatched transcriptions have been proposed as a mean to acquire probabilistic transcriptions from non-native speakers of a language.Prior work has demonstrated the value of these transcriptions by successfully adapting cross-lingual ASR systems for different tar-get languages.
arxiv
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Transcription-associated mutation promotes RNA complexity in highly expressed genes - a major new source of selectable variation [PDF]
, 2018 Alternatively spliced transcript isoforms are thought to play a critical role for functional diversity. However, the mechanism generating the enormous diversity of spliced transcript isoforms remains unknown, and its biological significance remains ...
Bruford, Michael W. +9 more
core +2 more sources
Deep Unsupervised Drum Transcription [PDF]
arXiv, 2019 We introduce DrummerNet, a drum transcription system that is trained in an unsupervised manner. DrummerNet does not require any ground-truth transcription and, with the data-scalability of deep neural networks, learns from a large unlabeled dataset. In DrummerNet, the target drum signal is first passed to a (trainable) transcriber, then reconstructed ...
arxiv
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Autoregulation of the Escherichia coli melR promoter: repression involves four molecules of MelR [PDF]
, 2008 The Escherichia coli MelR protein is a transcription activator that autoregulates its own promoter by repressing transcription initiation. Optimal repression requires MelR binding to a site that overlaps the melR transcription start point and to upstream
Belyaeva +41 more
core +4 more sources
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source
Gene gating at nuclear pores prevents the formation of R loops [PDF]
, 2017 Transcription is an important source of genetic variability. A large amount of transcription-associated genome variation arises from the unscheduled formation of R loops.
Aguilera López, Andrés +2 more
core +1 more source
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
Molecular Oncology, EarlyView.In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi +3 more
wiley +1 more source
, 1994 In this paper I report on an investigation into the problem of assigning tones to pitch contours. The proposed model is intended to serve as a tool for phonologists working on instrumentally obtained pitch data from tone languages.
Bird, Steven
core +1 more source