Chromatin regulation at the frontier of synthetic biology [PDF]
, 2015 As synthetic biology approaches are extended to diverse applications throughout medicine, biotechnology and basic biological research, there is an increasing need to engineer yeast, plant and mammalian cells.
Collins, James J. +3 more
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Transcription activator‐like effector nucleases efficiently disrupt the target gene in Iberian ribbed newts (
, 2013 Toshinori Hayashi +8 more
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Targeted Gene Disruption in Zebrafish Reveals Noncanonical Functions of LH Signaling in Reproduction [PDF]
, 2014 The pivotal role of gonadotropin signaling in regulating gonadal development and functions has attracted much research attention in the past 2 decades. However, the precise physiological role of gonadotropin signaling is still largely unknown in fish. In
Cheng, CHK (reprint author), Chinese Univ Hong Kong, Sch Biomed Sci, Shatin, Hong Kong, Peoples R China. +5 more
core +1 more source
Advances in biotechnology: genomics and genome editing [PDF]
, 2017 Genomics, the study of genes, their functions and related techniques has become a crucial science for developing understanding of life processes and how they evolve.
Beccari, Tommaso +4 more
core +1 more source
The therapeutic landscape of HIV-1 via genome editing
AIDS Research and Therapy, 2017 Current treatment for HIV-1 largely relies on chemotherapy through the administration of antiretroviral drugs. While the search for anti-HIV-1 vaccine remain elusive, the use of highly active antiretroviral therapies (HAART) have been far-reaching and ...
Alexander Kwarteng +2 more
doaj +1 more source
Transcription activator-like effector nucleases (TALENs) to eliminate mitochondria-specific mutant DNA [PDF]
, 2013 openalex +1 more source
The physicist's guide to one of biotechnology's hottest new topics: CRISPR-Cas
, 2018 Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated proteins (Cas) constitute a multi-functional, constantly evolving immune system in bacteria and archaea cells.
Bonomo, Melia E., Deem, Michael W.
core +1 more source
Structural organization, expression, and functional characterization of the murine cytomegalovirus immediate-early gene 3. [PDF]
, 1992 We have previously defined ie3 as a coding region located downstream of the ie1 gene which gives rise to a 2.75-kb immediate-early (IE) transcript. Here we describe the structural organization of the ie3 gene, the amino acid sequence of the gene product,
Bühler, Bernhard +3 more
core +1 more source
Correction: Targeting of the Plzf Gene in the Rat by Transcription Activator-Like Effector Nuclease Results in Caudal Regression Syndrome in Spontaneously Hypertensive Rats. [PDF]
PLoS One, 2020 Liška F +12 more
europepmc +1 more source
Histone deacetylases inhibitor and RAD51 recombinase increase transcription activator-like effector nucleases-mediated homologous recombination on the bovine β-casein gene locus [PDF]
, 2019 Da Som Park +3 more
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