Results 201 to 210 of about 27,079 (225)
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Transcription activator-like effector nucleases mediated metabolic engineering for enhanced fatty acids production in Saccharomyces cerevisiae

Journal of Bioscience and Bioengineering, 2015
Targeted engineering of microbial genomes holds much promise for diverse biotechnological applications. Transcription activator-like effector nucleases (TALENs) and clustered regularly interspaced short palindromic repeats/Cas9 systems are capable of efficiently editing microbial genomes, including that of Saccharomyces cerevisiae. Here, we demonstrate
Mustapha Aouida   +6 more
openaire   +4 more sources

Generation of Foxo3‐targeted Mice by Injection of mRNAs Encoding Transcription Activator‐like Effector Nucleases (TALENs) into Zygotes

Reproduction in Domestic Animals, 2015
ContentsIn this study, for exploring the mechanism of forkhead box O3(Foxo3) participating in regulation of the activation of primordial oocytes, Foxo3‐targeted mice were generated by injection of mRNAs encoding transcription activator‐like effector nucleases (TALENs) into mouse zygotes.
J Liu   +9 more
openaire   +3 more sources

Therapeutic strategies targeting FOXO transcription factors

Nature Reviews Drug Discovery, 2021
Eric W-f Lam   +2 more
exaly  

Advances in targeting ‘undruggable’ transcription factors with small molecules

Nature Reviews Drug Discovery, 2021
Angela N Koehler   +2 more
exaly  

Avidity in antibody effector functions and biotherapeutic drug design

Nature Reviews Drug Discovery, 2022
Simone C Oostindie   +2 more
exaly  

A review of cancer immunotherapy toxicity

Ca-A Cancer Journal for Clinicians, 2020
Lucy Boyce Kennedy
exaly  

Advances in the assessment and control of the effector functions of therapeutic antibodies

Nature Reviews Drug Discovery, 2011
Shan Chung, Esam I Azhar, Uwe Pühse
exaly  

NR4A transcription factors limit CAR T cell function in solid tumours

Nature, 2019
Hyungseok Seo   +2 more
exaly  

Eukaryotic core promoters and the functional basis of transcription initiation

Nature Reviews Molecular Cell Biology, 2018
Vanja Haberle, Alexander Stark
exaly  

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