Results 241 to 250 of about 11,860 (282)

Efficient genome editing in Pseudomonas syringae pv. actinidiae using the CRISPR/FnCas12a system. [PDF]

Mol Hortic
Gou Z, Wang Y, Qin C, Yan F, Du X, Xu Z, Zhu B, Liu P, Zhou H, Chen G.   +9 more
europepmc   +1 more source

Advances in genome editing in plants within an evolving regulatory landscape, with a focus on its application in wheat breeding. [PDF]

J Plant Biochem Biotechnol
Brock N, Kaur N, Halford NG.
europepmc   +1 more source

Multiplex engineering and multifunction T cells for precise and effective immunotherapies. [PDF]

Front Immunol
Jafarzadeh L, Smaani A, Delisle JS.
europepmc   +1 more source

CRISPR activation: identifying and using novel genes for plant disease resistance breeding. [PDF]

Front Genome Ed
McLaughlin JE, Kue Foka IC, Lawton MA, Di R.   +3 more
europepmc   +1 more source

RNAa-Mediated Gene Activation in the Regulation of Stem Cell Fate. [PDF]

Biomolecules
Lee H, Moon J, Kim SK.
europepmc   +1 more source

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Polyethylenimine-Mediated CCR5 Gene Knockout Using Transcription Activator-Like Effector Nucleases

Journal of Biomedical Nanotechnology, 2018
CCR5 acts as one of the key coreceptors for human immunodeficiency virus infection, which leads to acquired immune deficiency syndrome. CCR5 gene knockout comes up as an alternative method for treatment of the disease. Transcription activator-like effector nuclease is a powerful gene editing tool characterized by the ease of design, high rates of ...
Lian, Jin, Yan, Deng, Nongyue, He, Lijun, Wang, Mengling, Weng   +4 more
openaire   +2 more sources

Genome Editing Using Zinc-Finger Nucleases (ZFNs) and Transcription Activator-Like Effector Nucleases (TALENs)

2014
Targetable nucleases, including zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated (Cas), induce DNA double-strand breaks (DSBs) into user-defined sites. DSBs are immediately repaired through the evolutionarily conserved pathways
Hiroshi Ochiai, Takashi Yamamoto
openaire   +1 more source

Genome Modification of Pluripotent Cells by Using Transcription Activator-Like Effector Nucleases (TALENs)

2015
Interest is increasing in transcription activator-like effector nucleases (TALENs) as a tool to introduce targeted double-strand breaks into the large genomes of human and animal cell lines. The produced DNA lesions stimulate DNA repair pathways, error-prone but dominant non-homologous end joining (NHEJ) and accurate but less occurring homology ...
Amir, Taheri-Ghahfarokhi, Luis F, Malaver-Ortega, Huseyin, Sumer   +2 more
openaire   +2 more sources