Results 81 to 90 of about 15,248,084 (403)

Myocyte enhancer factor 2C: an osteoblast transcription factor identified by DMSO enhanced mineralization [PDF]

, 2011
Free to read on publisher website Rapid mineralization of cultured osteoblasts could be a useful characteristic in stem-cell mediated therapies for fracture and other orthopaedic problems. Dimethyl sulfoxide (DMSO) is a small amphipathic solvent molecule
Bacic-Welsh, Desa, Hobbs, Carl, Hutmacher, Dietmar, Morrison, Nigel, Stephens, Alexandre, Stephens, Sebastien, Woodruff, Mia   +6 more
core   +2 more sources

MatInspector and beyond: promoter analysis based on transcription factor binding sites

Bioinform., 2005
MOTIVATION Promoter analysis is an essential step on the way to identify regulatory networks. A prerequisite for successful promoter analysis is the prediction of potential transcription factor binding sites (TFBS) with reasonable accuracy.
Cartharius K, Frech K, Grote K, Klocke B, Haltmeier M, Klingenhoff A, Frisch M, Bayerlein M, Werner T, Kerstin Cartharius   +9 more
semanticscholar   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Pea3 transcription factor promotes neurite outgrowth

Frontiers in Molecular Neuroscience, 2014
Pea3 subfamily of ETS transcription factors consist of three major proteins, Pea3, ERM and ER81. Although important for many different tissues that exhibit branching morphogenesis, the function of Pea3 family in nervous system development and ...
BASAK eKANDEMIR, BERRAK eCAGLAYAN, BARBARA eHAUSOTT, BURCU eERDOGAN, UGUR eDAG, OZLEM eDEMIR, MELIS eSAVASAN SOGUT, Lars eKlimaschewski, ISIL eAKSAN KURNAZ   +8 more
doaj   +1 more source

Splicing factor 3B subunit 1 interacts with HIV Tat and plays a role in viral transcription and reactivation from latency [PDF]

, 2018
The main obstacle to an HIV cure is the transcriptionally inert proviruses that persist in resting CD4 T cells and other reservoirs. None of the current approaches has significantly reduced the size of the viral reservoir.
Kyei, George B, Lagisetti, Chandraiah, Meng, Shanshan, Niu, Austin, Ramani, Rashmi, Ratner, Lee, Webb, Thomas R   +6 more
core   +2 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

JASPAR 2016: a major expansion and update of the open-access database of transcription factor binding profiles

Nucleic Acids Res., 2015
JASPAR (http://jaspar.genereg.net) is an open-access database storing curated, non-redundant transcription factor (TF) binding profiles representing transcription factor binding preferences as position frequency matrices for multiple species in six ...
Anthony Mathelier, O. Fornes, David J. Arenillas, Chih-Yu Chen, Grégoire Denay, Jessica J. Y. Lee, Wenqiang Shi, C. Shyr, Ge Tan, R. Worsley-Hunt, Allen W. Zhang, F. Parcy, B. Lenhard, A. Sandelin, W. Wasserman   +14 more
semanticscholar   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

Transcription Factor Networks in Drosophila melanogaster

Cell Reports, 2014
Specific cellular fates and functions depend on differential gene expression, which occurs primarily at the transcriptional level and is controlled by complex regulatory networks of transcription factors (TFs).
David Y. Rhee, Dong-Yeon Cho, Bo Zhai, Matthew Slattery, Lijia Ma, Julian Mintseris, Christina Y. Wong, Kevin P. White, Susan E. Celniker, Teresa M. Przytycka, Steven P. Gygi, Robert A. Obar, Spyros Artavanis-Tsakonas   +12 more
doaj   +1 more source

Subfunctionalization of Paralog Transcription Factors Contributes to Regulation of Alkaloid Pathway Branch Choice in Catharanthus roseus

Frontiers in Plant Science, 2021
Catharanthus roseus produces a diverse range of specialized metabolites of the monoterpenoid indole alkaloid (MIA) class in a heavily branched pathway. Recent great progress in identification of MIA biosynthesis genes revealed that the different pathway ...
Maite Colinas, Maite Colinas, Jacob Pollier, Jacob Pollier, Dries Vaneechoutte, Dries Vaneechoutte, Deniz G. Malat, Deniz G. Malat, Fabian Schweizer, Fabian Schweizer, Liesbeth De Milde, Liesbeth De Milde, Rebecca De Clercq, Rebecca De Clercq, Joana G. Guedes, Joana G. Guedes, Joana G. Guedes, Teresa Martínez-Cortés, Francisco J. Molina-Hidalgo, Francisco J. Molina-Hidalgo, Mariana Sottomayor, Mariana Sottomayor, Klaas Vandepoele, Klaas Vandepoele, Alain Goossens, Alain Goossens   +25 more
doaj   +1 more source