Results 61 to 70 of about 1,314,675 (307)

ELAN development, keeping pace with communities' needs [PDF]

, 2012
ELAN is a versatile multimedia annotation tool that is being developed at the Max Planck Institute for Psycholinguistics. About a decade ago it emerged out of a number of corpus tools and utilities and it has been extended ever since.
Sloetjes, H., Somasundaram, A.
core   +1 more source

Lactylation of HMGB1 at K177 Drives Nuclear Export of TIAR to Promote Hypoxia‐Induced Stress Granule Formation

Advanced Science, EarlyView.
This study uncovers a novel mechanism in which p300‑catalyzed lactylation of HMGB1 triggers nuclear export of the HMGB1‐TIAR complex, driving TIAR‐dependent SGs formation in the cytoplasm. Mass spectrometry and mutagenesis reveals that K177 lactylation is essential for this export and subsequent SGs formation.
Chengyu Li, Zhaojun Liu, Linjie Zhu, Gang Wu, Chen Fu, Hongmin Li, Tong He, Ming Shen, Honglin Liu   +8 more
wiley   +1 more source

An Attentional Model for Speech Translation Without Transcription

North American Chapter of the Association for Computational Linguistics, 2016
For many low-resource languages, spoken language resources are more likely to be annotated with translations than transcriptions. This bilingual speech data can be used for word-spotting, spoken document retrieval, and even for documentation of ...
Long Duong, Antonios Anastasopoulos, David Chiang, Steven Bird, Trevor Cohn   +4 more
semanticscholar   +1 more source

Mesenchymal Stromal Cells Play an Analgesic Role Through a Npy2r Sensory Neuron‐Mediated Lung‐to‐Brain Axis

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSC) are considered a promising alternative for neuropathic pain (NP) treatment, but underlying mechanisms remain elusive. Huang et al. illustrate that a Npy2r sensory neuron‐related lung–brain axis contributes to MSC analgesia.
Jing Huang, Taihe Zhou, Yueming Sun, Yuanchen Ma, Yiwen Deng, Keyu Chen, Ruijie Li, Yuan Qiu, Tao Wang, Xiaoyong Chen, Li Huang, Lu Zhu, Xueyi Tu, Ying Wang, Zheming Liu, Rouchen Lin, Yunli Tong, Yuantao Li, Heshe Li, Lin Nie, Rui Fang, Jianqi Feng, Xuhong Wei, Xia Feng, Andy Peng Xiang, Xiaoran Zhang   +25 more
wiley   +1 more source

Decoding Handwriting Trajectories from Intracortical Brain Signals for Brain‐to‐Text Communication

Advanced Science, EarlyView.
By developing a novel framework that optimizes both shape and temporal loss during decoder training, the authors successfully reconstruct human‐recognizable handwriting trajectories from intracortical neural signals for both Chinese characters and English letters, effectively resolving the temporal misalignment problem in clinical BCIs, thereby ...
Guangxiang Xu, Zebin Wang, Kedi Xu, Junming Zhu, Jianmin Zhang, Yueming Wang, Yaoyao Hao   +6 more
wiley   +1 more source

CGRP‐Loaded ROS‐Responsive Hydrogel Restores Neuro‐Angiogenic Signaling to Promote Bone Regeneration in Diabetes‐Associated Periodontitis

Advanced Science, EarlyView.
This study shows that diabetes damages sensory nerve fibers, especially CGRP‐positive ones, in the periodontium and disrupts autophagy in trigeminal ganglion neurons, affecting bone homeostasis by inhibiting type H vessel formation. To address this, CGRP@PVA/tsPBA hydrogels are developed to release CGRP in response to ROS, which binds to endothelial ...
Chaoning Zhan, Qingyi Dai, Jianhan Ren, Lijian Jin, Weiping Wang, Zhou Ye, James Kit Hon Tsoi, Yifan Lin   +7 more
wiley   +1 more source

Engineering Adenine Deaminase TadA for Precise and PAM‐Flexible Point Mutagenesis and Gradient‐Tuning Endogenous Protein Design

Advanced Science, EarlyView.
Base editing enables precise nucleotide substitutions but limited by bystander editing. This study engineers plant base editors by fusing optimized TadA variants with PAM‐flexible SpRY nickase, enabling A‐to‐G, C‐to‐T, and dual‐base conversions in a highly condensed window (≤3 nucleotides). Additionally, TadDBE (TadA Dual‐Base Editor)‐mediated directed
Kangli Sun, Si Cheng, Nan Chai, Jianing Mi, Ruixiang Zhang, Qian Qian, Zhiye Zheng, Ke Chen, Dongchang Zeng, Xin Peng, Mengyuan Shen, Degui Zhou, Qinlong Zhu, Qi Liu, Jiantao Tan   +14 more
wiley   +1 more source

Recent Advancements in Topic Modeling Techniques for Healthcare, Bioinformatics, and Other Potential Applications

Advanced Intelligent Systems, EarlyView.
This article offers a comprehensive review of topic modeling techniques, tracing their evolution from inception to recent developments. It explores methods such as latent Dirichlet allocation, latent semantic analysis, non‐negative matrix factorization, probabilistic latent semantic analysis, Top2Vec, and BERTopic, highlighting their strengths ...
Pratima Kumari, Sachin Kadian, Mukund Vora, Pradyumna Vemuri, Sumit Kumar, Om Prakash Verma, Roger J. Narayan   +6 more
wiley   +1 more source

Philanthropy and Indigenous Initiatives: Insights From Australian Donors

Australian Journal of Social Issues, EarlyView.
ABSTRACT This paper draws on a survey and interview data, collected from a group of 180 donors who made monetary gifts to an Australian higher education institution, to better understand what drives individuals and organisations to donate to Indigenous initiatives.
Celina McEwen, Christopher Bajada, Deborah Cotton, Kevin Wallace, David S. Waller   +4 more
wiley   +1 more source

Relationships and Identity: An Ethnographic Study With Young People in South‐East Queensland Who Had Left Out‐Of‐Home Care

Australian Journal of Social Issues, EarlyView.
ABSTRACT Young people who transition to adulthood while transitioning from out‐of‐home care, like their peers not in care may face several challenges in early adulthood. These include, high housing costs, fixed (often low) incomes, limited access to jobs and further education, developing and consolidating personal relationships and pressures from ...
Madonna Boman
wiley   +1 more source