A Phosphorylation‐Induced Micellization Switch in the Low‐Complexity Domain of TDP‐43
Phosphorylation of TAR DNA‐binding protein's 43 kDa (TDP‐43) low‐complexity domain by casein kinase 1 delta (CK1δ) acts as a molecular switch, redirecting its self‐assembly from macroscopic phase separation toward finite‐sized, spherical block‐copolymer micelles of ∼30 nm.
Rodrigo F. Dillenburg +16 more
wiley +1 more source
Complex sporulation-specific expression of transcription termination factor Rho highlights its involvement in Bacillus subtilis cell differentiation. [PDF]
Bidnenko V +9 more
europepmc +1 more source
Furrow tillage resolves the conventional‐vs.‐no‐tillage trade‐off by simultaneously cutting CO2 efflux to 2.0–3.0 g C m−2 d−1 and unlocking high nutrient availability for the rice rhizosphere. This scalable agronomic solution strengthens soil health, enhances plant physiology, reshapes microbial metabolism, and shifts paddy systems toward a net ...
Arnab Majumdar +10 more
wiley +1 more source
Protein phosphatase PP1 regulation of RNA polymerase II transcription termination and allelic exclusion of VSG genes in trypanosomes. [PDF]
Kieft R +4 more
europepmc +1 more source
In MYC‐enforced B‐cell lymphoma, SOX5 occupies promoter‐proximal regulatory regions and is associated with reduced chromatin accessibility at the PCNP locus. PCNP repression promotes proliferative remodeling by limiting apoptosis and cell‐cycle restraint.
Yiyou Mao +6 more
wiley +1 more source
HD‐tDCS promotes recovery after intracerebral hemorrhage by enhancing PPARγ‐dependent astrocyte remodeling in a mouse model of ICH. This process suppresses proinflammatory astrocytic activation, restores perivascular AQP4 repolarization, and improves glymphatic influx and efflux, thereby facilitating hematoma and perihematomal edema clearance and ...
Zhiming Li +8 more
wiley +1 more source
Direct and indirect control of Rho-dependent transcription termination by the <i>Escherichia coli lysC</i> riboswitch. [PDF]
Ghosh T +7 more
europepmc +1 more source
A widely conserved protein Rof inhibits transcription termination factor Rho and promotes Salmonella virulence program. [PDF]
Zhang J +14 more
europepmc +1 more source
Single-molecule characterization of Sen1 translocation properties provides insights into eukaryotic factor-dependent transcription termination. [PDF]
Wang S, Han Z, Strick TR.
europepmc +1 more source

