Results 211 to 220 of about 4,769,934 (397)

Tyrosine kinase oncogenes abrogate interleukin-3 dependence of murine myeloid cells through signaling pathways involving c-myc: conditional regulation of c-myc transcription by temperature-sensitive v-abl. [PDF]

, 1989
John L. Cleveland, Michael Dean, Naomi Rosenberg, Jean Y. J. Wang, U R Rapp   +4 more
openalex   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Structural insights into transcriptional regulation by the helicase RECQL5. [PDF]

Nat Struct Mol Biol
Florez Ariza AJ, Lue NZ, Grob P, Kaeser B, Fang J, Kassube SA, Nogales E.   +6 more
europepmc   +1 more source

Regulation of polyomavirus transcription by large tumor antigen.

, 1984
William G. Farmerie, William R. Folk
openalex   +1 more source

Post-transcriptional gene regulation by mRNA modifications

Nature reviews. Molecular cell biology, 2016
B. Zhao, I. A. Roundtree, Chuan He
semanticscholar   +1 more source

Beyond cytotoxic T cells: reprogrammed regulatory T cells help facilitate response to dual checkpoint blockade

Molecular Oncology, EarlyView.
Rolig, Peng, and colleagues have shed new light on how dual blockade of PD1 and LAG3 enhances antitumor immunity. They found that response to immunotherapy with anti‐PD1 + anti‐LAG3 was associated with reprogramming of canonically suppressive CD4+ regulatory T cells to an inflammatory state.
Tullia C. Bruno, Anthony R. Cillo
wiley   +1 more source

Transcriptional regulation by PHGDH drives amyloid pathology in Alzheimer's disease. [PDF]

Cell
Chen J, Hadi F, Wen X, Zhao W, Xu M, Xue S, Lin P, Calandrelli R, Richard JLC, Song Z, Li J, Amani A, Liu Y, Chen X, Zhong S.   +14 more
europepmc   +1 more source

Sequence organisation and transcriptional regulation of the mouse elastase II and trypsln genes

, 1986
Brian J. Stevenson, Otto Hagenbüchle, Peter K. Wellauer   +2 more
openalex   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

A lethal deletion on mouse chromosome 7 affects regulation of liver-cell-specific functions: posttranscriptional control of serum protein and transcriptional control of aldolase B synthesis. [PDF]

, 1985
J M Sala-Trepat, Maryse Poiret, Carole H. Sellem, R. Bessada, T. Erdös, Salome Gluecksohn‐Waelsch   +5 more
openalex   +1 more source