Results 151 to 160 of about 8,622 (220)
Tomato plants control leaf sodium levels to limit damage by Spodoptera littoralis larvae
New Phytologist, Volume 250, Issue 5, Page 3417-3427, June 2026.Summary Sodium is an essential element for animal growth and survival. Here we test the hypothesis that plants exposed to insect feeding can translocate sodium from the feeding site to other plant organs as a defense strategy against phytophagous insects, which need sodium in their diet.
Valerio Cirillo +12 more
wiley +1 more source
The Outcome of Intracellular Selenomonas sputigena and its Impact on Gingival Keratinocytes
Molecular Oral Microbiology, Volume 41, Issue 3, Page 131-144, June 2026.ABSTRACT Selenomonas sputigena is an understudied oral pathobiont associated with periodontitis and dental caries. We recently demonstrated that S. sputigena binds to gingival epithelial cells (GECs), where afterwards the bacterium causes robust in vitro pro‐inflammatory cytokine production and migration of monocytes and neutrophils.
Colin G. Hawkes +6 more
wiley +1 more source
Tissue Engineered Human Elastic Cartilage From Primary Auricular Chondrocytes for Ear Reconstruction
Advanced Functional Materials, Volume 36, Issue 36, 4 May 2026.Despite over three decades of research, no tissue‐engineered solution for auricular reconstruction in microtia patients has reached clinical translation. The key challenge lies in generating functional elastic cartilage ex vivo. Here, we integrate synergistic cell‐biomaterial strategies to engineer auricular grafts with mechanical and histological ...
Philipp Fisch +13 more
wiley +1 more source
MVP Inhibits Influenza A Virus‐Induced Ferroptosis by Targeting IRF1 and Increasing FSP1 Activity
Advanced Science, Volume 13, Issue 26, 8 May 2026.During IAV infection, MVP inhibits IRF1 polyubiquitination, thereby relieving IRF1‐mediated transcriptional inhibition of FSP1. Consequently, this leads to an upregulation of FSP1 expression, thereby reinforcing the inhibition of ferroptosis. In addition, the MVP can promote myristoylation and ubiquitination of FSP1, enabling its membrane localization ...
Yingbo Chen +12 more
wiley +1 more source
American Journal of Medical Genetics Part A, Volume 200, Issue 5, Page 1098-1104, May 2026.ABSTRACT The KDM2B‐related neurodevelopmental disorder is a recently identified Mendelian disorder of the epigenetic machinery associated with pathogenic variants in KDM2B. Global developmental delay, intellectual disability, congenital anomalies, and systemic manifestations characterize the disorder.
Adriana Gomes +3 more
wiley +1 more source
Abi3S212F Alzheimer's disease variant alters plaque structure and disrupts microglia
Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.Abstract BACKGROUND Genetic variants affecting microglial function can influence Alzheimer's disease (AD) risk, yet the underlying mechanisms remain unclear. The AD‐associated ABI3S209F (Abi3S212F in mouse) variant regulates cytoskeletal dynamics, but its in vivo impact on pathology is unknown. METHODS: An Abi3S212F mouse was developed and crossed with
Claire A. Butler +29 more
wiley +1 more source
CNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.The schematic summarizes SESN2's neuroprotective actions after subarachnoid hemorrhage. SESN2 activates an AMPK/PGC1α/Nrf2 signaling cascade that reduces oxidative stress, suppresses neuronal ferroptosis, and improves functional outcomes; these effects were validated by genetic knockdown and pharmacologic inhibition.
Yi Zhang +9 more
wiley +1 more source
Abundance, arrangement, and function of sequence motifs in the chicken promoters [PDF]
, 2014 core +1 more source
Conservation of Neuron‐Astrocyte Correlated Activity in Developing Sensory Pathways
Glia, Volume 74, Issue 5, May 2026.Astrocytes and neurons in the superior colliculus exhibit spatiotemporal correlated activity before eye opening. Each neuronal wave is followed by a calcium wave in astrocytes. Spillover of glutamate activates mGluR5 and mGluR3 in astrocytes. ABSTRACT Neurons in developing sensory organs exhibit prolonged burst firing before the onset of sensory ...
Vered Kellner +8 more
wiley +1 more source
Chimeric RNA isoforms generated by diverse mechanisms from two C-type lectins modulate innate immunity in arthropods. [PDF]
Proc Natl Acad Sci U S AHuang Y, Huang X, Zhang LH, Ren Q.
europepmc +1 more source