Results 151 to 160 of about 6,140 (191)

Single-cell transcriptome-wide Mendelian randomization and colocalization analyses uncover cell-specific mechanisms in atherosclerotic cardiovascular disease. [PDF]

Am J Hum Genet
Ray A, Alabarse P, Malik R, Sargurupremraj M, Bernhagen J, Dichgans M, Baumeister SE, Georgakis MK.   +7 more
europepmc   +1 more source

A Genome-Wide Association Study of Anti-Müllerian Hormone (AMH) Levels in Samoan Women. [PDF]

Genes (Basel)
Erdogan-Yildirim Z, Carlson JC, Krishnan M, Zhang JZ, Lambert-Messerlian G, Naseri T, Viali S, Hawley NL, McGarvey ST, Weeks DE, Minster RL.   +10 more
europepmc   +1 more source

A novel reusable transcriptome-wide association study workflow used to map key genes linked to important cattle traits

Jayaraman S, Chitneedi PK, Kadri NK, Costa-Monteiro-Moreira G, Salavati M, Charlier C, Boichard D, Sanchez M, Pausch H, Kühn C, Prendergast J, Clark E.   +11 more
europepmc   +1 more source

Multitrait transcriptome‐wide association study (TWAS) tests

Genetic Epidemiology, 2021
Multitrait tests can improve power to detect associations between individual single‐nucleotide polymorphisms (SNPs) and several related traits. Here, we develop methods for multi‐SNP transcriptome‐wide association (TWAS) tests to test the association ...
Helian Feng, Nicholas Mancuso, Bogdan Paşaniuc, Peter Kraft   +3 more
openalex   +2 more sources

Abstract 30: Cross-cancer cross-tissue transcriptome-wide association study (TWAS) of 11 cancers identifies 56 novel genes

Epidemiology, 2020
Although cancer is a heterogeneous disease, there are shared hallmark mechanisms across multiple tumor types. Because of this, identifying genes associated with multiple cancer types has the potential to shed light on general oncogenic mechanisms ...
Helian Feng, Arunabha Majumdar, Bogdan Paşaniuc, Hongjie Chen, Sara Lindström, Jeroen R. Huyghe, Stephanie L. Schmit, Tracy A. O’Mara, Deborah J. Thompson, Stuart MacGregor, Paul Brennan, James McKay, Richard S. Houlston, Beatrice Melin, Christopher I. Amos, Anne E. Cus, Mark M. Iles, Siddhartha Kar, Paul D.P. Pharoah, Rayjean J. Hung, Peter Kraft   +20 more
openalex   +2 more sources

Abstract 1591: Large-scale transcriptome-wide association study (TWAS) identifies novel candidate susceptibility genes for pancreatic cancer

Epidemiology, 2019
Jun Zhong, Ashley Jermusyk, Lang Wu, Jason W. Hoskins, Irene Collins, Mingfeng Zhang, Lei Song, Charles C. Chung, Tongwu Zhang, Wenming Xiao, Rachael Z. Stolzenberg‐Solomon, Alison P. Klein, Brian M. Wolpin, Xiao‐Ou Shu, Stephen J. Chanock, Sara H. Olson, Nilanjan Chatterjee, Jill P. Smith, Jianxin Shi, Peter Kraft, Gloria M. Petersen, Wei Zheng, Laufey T. Ámundadóttir   +22 more
semanticscholar   +3 more sources

Transcriptome-wide association study (TWAS) of nasal respiratory epithelium and childhood asthma

Paediatric asthma and allergy, 2019
Erick Forno, Rong Zhang, Yale Jiang, Qi Yan, Yueh‐Ying Han, Edna Acosta‐Pérez, Nadia Boutaoui, Glorisa Canino, Wei Chen, Juan C. Celedón   +9 more
openalex   +2 more sources

A-TWAS: An aggregated transcriptome-wide association study model incorporating multiple Bayesian priors

bioRxiv
Yong Liang, Handong Wang, Yan Zhang
openalex   +2 more sources

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Brain transcriptome-wide association study implicates novel risk genes underlying schizophrenia risk

Psychological Medicine, 2023
Background To identify risk genes whose expression are regulated by the reported risk variants and to explore the potential regulatory mechanism in schizophrenia (SCZ).
Chengcheng Zhang, Xiao-jing Li, Lian-sheng Zhao, Wan-jun Guo, W. Deng, Qiang Wang, Xun Hu, Xiangdong Du, P. Sham, Xiongjian Luo, Tao Li   +10 more
semanticscholar   +1 more source

Identification of candidate genes associated with milk production and mastitis based on transcriptome-wide association study.

Animal Genetics
Genetic research for the assessment of mastitis and milk production traits simultaneously has a long history. The main issue that arises in this context is the known existence of a positive correlation between the risk of mastitis and lactation ...
Sevda Hosseinzadeh, Seyed Abbas Rafat, Arash Javanmard, Lingzhao Fang   +3 more
semanticscholar   +1 more source