Results 171 to 180 of about 602,244 (307)

Biofilm‐Binding Phages Enhance Biofilm Eradication by Synergistic Photothermal and Photodynamic Therapy

Advanced Science, EarlyView.
Engineered phage‐based trifunctional nanofibers are developed for synergistic biofilm eradication. Biofilm‐binding phages, armed with AuNPs and TCPP, serve as both warheads and scaffolds, endowing the phototherapy agents with biofilm‐anchoring ability. Upon light irradiation, AuNPs induce photothermal therapy, while TCPP generates 1O2 for photodynamic ...
Ying Cao, Tao Yang, Rui Wang, Hui‐Da Li, Xiao‐Yu Zhang, Feng Cheng, Ying Liu, Jian‐Hua Wang, Ting Yang, Chuanbin Mao   +9 more
wiley   +1 more source

Functional Annotation of Coding Sequences in the Cyanogenic Millipede Cherokia georgiana. [PDF]

Sci Data
Cruz E, Carter S, Hastings D, Snyder BA, Sengupta A.   +4 more
europepmc   +1 more source

Optimized Ex Vivo Human Liver Slice Culture Maintains Extended Viability and Function for Hepatotoxicity Testing

Advanced Science, EarlyView.
An optimized ex vivo human liver slice culture system preserves tissue architecture, hepatocyte function, and immune‐stromal complexity for at least five days. By refining slice thickness, oxygenation, air‐liquid interface, and extracellular matrix support, the platform enables human‐relevant hepatotoxicity testing and mechanistic studies, offering a ...
Huiche Feng, Cinzia Esposito, Andrej Benjak, Matthias S. Matter, Miriam Cieri, Camilla De Carlo, Philipp Sedlaczek, Fabian Haak, Mattia Marinucci, Gabriel Fridolin Hess, Otto Kollmar, Mairene Coto‐Llerena, Luca Di Tommaso, Visar Vela, Lukas Bubendorf, Luigi M. Terracciano, Charlotte K. Y. Ng, Salvatore Piscuoglio   +17 more
wiley   +1 more source

Insights Into Spatial Transcriptomics: Exploring Recent Technical Developments and Their Diverse Applications. [PDF]

FASEB J
Li X, Yang Z, Li J, Cao H, Xu K, Shen J, Wang Y, Gomaa SE, Cheng G, Teng T, Li J, Wang X, Dong X.   +12 more
europepmc   +1 more source

<i>Arabidopsis</i> bZIP68 Modulates Flowering Time Potentially with Chromatin and Stress-Responsive Regulators. [PDF]

Biology (Basel)
Park C, Geem KR, Choi BY, Kim J.
europepmc   +1 more source

Stage‐Adaptive Janus Microneedle System for Redox‐Immune Regulation and Mitochondrial Protection in Infected Diabetic Wound Healing

Advanced Science, EarlyView.
ABSTRACT Infected diabetic wounds are sustained by a vicious cycle of hyperglycemia‐driven bacterial infection, persistent oxidative stress, and excessive inflammation, which collectively disrupt the ordered progression of tissue repair. Here, we engineered a stage‐adaptive Janus microneedle patch (MN‐FeSAC‐PPE) to enable a staged therapeutic process ...
Mengting Yin, Yu Zhang, Xinyu Qu, Jiayi Liu, Zhongyi Sun, Haibo Liu, Ziyan Chen, Jing Ru, Jingwen Han, Bingqiang Lu, Yan Lu, Yan Wang, Xinyu Zhao, Feng Chen   +13 more
wiley   +1 more source

Transcriptome-guided metabolic model states of denitrification PA14 biofilm subpopulations predicted NO-secretion rates and oxidative stress metabolic functions.

(A) Percentages of experimental denitrification-classified cells expressing nitrate reductases encoded by narG and napA. (B) Percentages of experimental denitrification-classified cells with high expression of narG and napA further classified with and ...
Mohammad Mazharul Islam (1819852), Tracy J. Kuper (18452180), Shayn M. Peirce-Cottler (12254549), Jason A. Papin (8721624), Roseanne M Ford (18452183)   +4 more
core   +1 more source

Transcriptomic analysis reveals members and expression characteristics of innate immunity genes in Chinese scorpion Mesobuthus martensii. [PDF]

Sci Rep
Wang H, Zhao Y, Yang Z, Zhang F, Di Z.
europepmc   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Identification-Based Comparative Proteomic and Peptidomic Profiling of <i>Vespa mandarinia</i> and <i>Apis mellifera</i> Venoms Supported by De Novo Transcriptomic Annotation. [PDF]

Toxins (Basel)
Yang L, Li L, Dao J, Yang L, Yang Q.
europepmc   +1 more source