Results 251 to 260 of about 963,153 (378)

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source

Spatial transcriptomics herald a new era of transcriptome research

Clinical and Translational Medicine, 2023
Dominik Saul, Robyn Laura Kosinsky
openaire   +3 more sources

Transcriptome datasets of wheat plant cultures treated with seed priming fertilizer. [PDF]

Data Brief
Decsi K, Ahmed M, Rizk R, Abdul-Hamid D, Tóth Z.   +4 more
europepmc   +1 more source

A green cell-cycle transcriptome [PDF]

, 2002
Jonathan B Weitzman
openalex   +1 more source

Microgravity-Induced Transcriptome Adaptation in Mouse Paraspinal longissimus dorsi Muscle Highlights Insulin Resistance-Linked Genes [PDF]

, 2017
Blottner, Dieter, Ciciliot, Stefano, Furlan, Sandra, Gambara, Guido, Gunga, Hanns Christian, Gutsmann, Martina, Salanova, Michele, Schiffl, Gudrun, Ungethuem, Ute, Volpe, Pompeo   +9 more
core   +1 more source

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

Advanced Science, EarlyView.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo, Yang Zhao, Xianle Rong, Chenxi Niu, Shiyu Hu, Qiang Liu, Fuping You   +6 more
wiley   +1 more source

Transcriptomic and Metabolomic Insights into Benzylisoquinoline Alkaloid Biosynthesis in Goldthread (<i>Coptis trifolia</i>). [PDF]

Int J Mol Sci
Koh YS, Zhu F, Hwang Y, Yoo MJ.
europepmc   +1 more source

The mammalian transcriptome [PDF]

, 2002
Jonathan B Weitzman
openalex   +1 more source

Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors

Cell, 2018
S. Konermann, Peter Lotfy, Nicholas J. Brideau, Jennifer Oki, M. Shokhirev, P. Hsu   +5 more
semanticscholar   +1 more source

An Allele of Glutamate Formiminotransferase Triggers 5‐Methyl‐Tetrahydrofolate‐to‐MeFox Conversion and Facilitates Folate Biofortification in Maize

Advanced Science, EarlyView.
This work demonstrates the distinct roles of the glutamate formiminotransferase (GFT) enzyme in plants. The GFT triggers the conversion of 5‐methyl‐tetrahydrofolate to MeFox in plants, a process distinct from its role as a formiminotransferase in mammals.
Tong Lian, Wenzhu Guo, Yanjing Wang, Weiwei Wen, Weixuan Wang, Ling Jiang, Qiuju Liang, Ji'an Liu, Haijun Liu, Yuan Xue, Lixu Pan, Qiaoquan Liu, Ping Yin, Delin Zhang, Jianbing Yan, Chunyi Zhang   +15 more
wiley   +1 more source