Results 21 to 30 of about 428,489 (261)

Human mast cell activation through Fc receptors and Toll-like receptors

open access: yesAllergology International, 2004
Mast cells express high-affinity IgE receptors (FcεRI) on their surface and can be activated to secrete a variety of biologically active mediators by cross-linking of receptor-bound IgE.
Yoshimichi Okayama   +7 more
doaj   +1 more source

BAT: Bisulfite Analysis Toolkit [version 1; referees: 2 approved]

open access: yesF1000Research, 2017
Here, we present BAT, a modular bisulfite analysis toolkit, that facilitates the analysis of bisulfite sequencing data. It covers the essential analysis steps of read alignment, quality control, extraction of methylation information, and calling of ...
Helene Kretzmer   +2 more
doaj   +1 more source

The Human Mitochondrial Transcriptome [PDF]

open access: yesCell, 2011
The human mitochondrial genome comprises a distinct genetic system transcribed as precursor polycistronic transcripts that are subsequently cleaved to generate individual mRNAs, tRNAs, and rRNAs. Here, we provide a comprehensive analysis of the human mitochondrial transcriptome across multiple cell lines and tissues.
Mercer, Tim R.   +11 more
openaire   +5 more sources

Fungal transcriptomics

open access: yesMicrobiological Research, 2007
We have now entered in the post-genomic era, where we have knowledge of plethora of fungal genomes and cutting edge technology is available to study global mRNA, protein and metabolite profiles. These so-called 'omic' technologies (transcriptomics, proteomics and metabolomics) provide the possibility to characterize plant-pathogen interactions and ...
Bhadauria, Vijai   +3 more
openaire   +2 more sources

And Now, Transcriptomics [PDF]

open access: yesNeuron, 2002
In this issue of Neuron, report different patterns of 5-HT2C pre-mRNA editing in suicide victims, as compared to controls. Treatment of mice with fluoxetine alters the pattern of 5-HT2C transcript editing in the direction opposite that observed for suicide victims.
openaire   +2 more sources

Palindrome-mediated Translocations in Humans: A New Mechanistic Model for Gross Chromosomal Rearrangements

open access: yesFrontiers in Genetics, 2016
Palindromic DNA sequences, which can form secondary structures, are widely distributed in the human genome. Although the nature of the secondary structure—single-stranded hairpin or double-stranded cruciform—has been extensively investigated in vitro ...
Hidehito Inagaki   +8 more
doaj   +1 more source

Expansion of the SOS regulon of Vibrio cholerae through extensive transcriptome analysis and experimental validation

open access: yesBMC Genomics, 2018
Background The SOS response is an almost ubiquitous response of cells to genotoxic stresses. The full complement of genes in the SOS regulon for Vibrio species has only been addressed through bioinformatic analyses predicting LexA binding box consensus ...
Evelyne Krin   +12 more
doaj   +1 more source

Analysis of splice variants of the human protein disulfide isomerase (P4HB) gene

open access: yesBMC Genomics, 2020
Background Protein Disulfide Isomerases are thiol oxidoreductase chaperones from thioredoxin superfamily with crucial roles in endoplasmic reticulum proteostasis, implicated in many diseases.
Daniela Kajihara   +9 more
doaj   +1 more source

Role of the Solute-Binding Protein CuaD in the Signaling and Regulating Pathway of Cellobiose and Cellulose Utilization in Ruminiclostridium cellulolyticum

open access: yesMicroorganisms, 2023
In Ruminiclostridium cellulolyticum, cellobiose is imported by the CuaABC ATP-binding cassette transporter containing the solute-binding protein (SBP) CuaA and is further degraded in the cytosol by the cellobiose phosphorylase CbpA.
Aurélie Fosses   +7 more
doaj   +1 more source

Fungal Transcriptomics

open access: yes, 2018
Transcriptomics, the study of RNA molecules, provides in-depth understanding of cellular functions and the genomic landscape of transcription. Transcriptomics refers to the study of all classes on RNA molecules including mRNA, tRNA, and siRNA. In this chapter, we specifically focus on mRNA, which encodes the protein-coding portion of the genomic DNA ...
Singan, Vasanth R   +2 more
openaire   +4 more sources

Home - About - Disclaimer - Privacy