Results 21 to 30 of about 451,072 (262)
BAT: Bisulfite Analysis Toolkit [version 1; referees: 2 approved]
F1000Research, 2017 Here, we present BAT, a modular bisulfite analysis toolkit, that facilitates the analysis of bisulfite sequencing data. It covers the essential analysis steps of read alignment, quality control, extraction of methylation information, and calling of ...
Helene Kretzmer +2 more
doaj +1 more source
The Human Mitochondrial Transcriptome [PDF]
Cell, 2011 The human mitochondrial genome comprises a distinct genetic system transcribed as precursor polycistronic transcripts that are subsequently cleaved to generate individual mRNAs, tRNAs, and rRNAs. Here, we provide a comprehensive analysis of the human mitochondrial transcriptome across multiple cell lines and tissues.
Mercer, Tim R. +11 more
openaire +5 more sources
Frontiers in Genetics, 2016 Palindromic DNA sequences, which can form secondary structures, are widely distributed in the human genome. Although the nature of the secondary structure—single-stranded hairpin or double-stranded cruciform—has been extensively investigated in vitro ...
Hidehito Inagaki +8 more
doaj +1 more source
Nephroprotective Potential of Tinospora cordifolia: Phytochemical Profiling and Antioxidant Protection Against Glucose-Induced Oxidative Stress [PDF]
BIO Web of ConferencesDiabetic nephropathy (DN), a microvascular complication of diabetes mellitus, represents a major cause of end-stage renal (ESRD) disease and is caused by hyperglycemia-induced oxidative stress and inflammation.
Yadav Sushma, Gauba Pammi, Rani Vibha
doaj +1 more source
Microbiological Research, 2007 We have now entered in the post-genomic era, where we have knowledge of plethora of fungal genomes and cutting edge technology is available to study global mRNA, protein and metabolite profiles. These so-called 'omic' technologies (transcriptomics, proteomics and metabolomics) provide the possibility to characterize plant-pathogen interactions and ...
Bhadauria, Vijai +3 more
openaire +2 more sources
And Now, Transcriptomics [PDF]
Neuron, 2002 In this issue of Neuron, report different patterns of 5-HT2C pre-mRNA editing in suicide victims, as compared to controls. Treatment of mice with fluoxetine alters the pattern of 5-HT2C transcript editing in the direction opposite that observed for suicide victims.
openaire +2 more sources
BMC Genomics, 2018 Background The SOS response is an almost ubiquitous response of cells to genotoxic stresses. The full complement of genes in the SOS regulon for Vibrio species has only been addressed through bioinformatic analyses predicting LexA binding box consensus ...
Evelyne Krin +12 more
doaj +1 more source
Microorganisms, 2023 In Ruminiclostridium cellulolyticum, cellobiose is imported by the CuaABC ATP-binding cassette transporter containing the solute-binding protein (SBP) CuaA and is further degraded in the cytosol by the cellobiose phosphorylase CbpA.
Aurélie Fosses +7 more
doaj +1 more source
Analysis of splice variants of the human protein disulfide isomerase (P4HB) gene
BMC Genomics, 2020 Background Protein Disulfide Isomerases are thiol oxidoreductase chaperones from thioredoxin superfamily with crucial roles in endoplasmic reticulum proteostasis, implicated in many diseases.
Daniela Kajihara +9 more
doaj +1 more source