Results 91 to 100 of about 6,405,169 (259)

Electrical Nerve Stimulation Can Be Used as a Tool in fMRI Studies of Pain- and Tingling-Evoked Activations

open access: yesPain Research and Management, 2000
OBJECTIVES/HYPOTHESES: To determine whether transcutaneous electrical nerve stimulation (TENS) provides adequate, inexpensive and simple means to image innocuous and pain-related activations in the thalamus and cortex.
Karen D Davis   +3 more
doaj   +1 more source

The Hypoalgesic Effects of Acupuncture-Like Transcutaneous Electrical Nerve stimulation (AL-TENS) Compared to Conventional TENS

open access: yes, 2008
Introduction: Transcutaneous electrical nerve stimulation (TENS) is used to reduce pain. TENS is applied as conventional TENS (50-100 Hz, causing paraesthesia) or acupuncture-like TENS (AL-TENS).
Francis, Richard Paul
core  

Glutaminolysis Blockade‐Empowered Bimodal Nanodepot for Spatially Complementary Sono‐Thermal Ablation via PANoptosis and STING Activation Against Large Tumors

open access: yesAdvanced Science, EarlyView.
An injectable bimodal TCPD nanodepot disrupts glutaminolysis and TCA metabolism, sensitizing large tumors to spatially complementary sono‐thermal ablation for complete treatment coverage. This intervention induces mitochondrial and endoplasmic reticulum dysfunction, genotoxicity, and NAD+ depletion, converging to trigger PANoptosome assembly and ...
Yi‐Ming Liu   +10 more
wiley   +1 more source

Effect of Transcutaneous Electrical Nerve Stimulation on Postoperative Pain and Patient Satisfaction

open access: yes, 2019
Background and Aims: This study was conducted to investigate the effect of transcutaneous electrical nerve stimulation on postoperative pain, changes in patients’ vital signs, and patient satisfaction after inguinal herniorrhaphy. Design: This study used
Karakaya E.   +7 more
core   +1 more source

Targeted‐Penetrating Biomimetic Hybrid Transfersomes for Enhanced Transdermal Gene Transfection in Hypertrophic Scar Therapy

open access: yesAdvanced Science, EarlyView.
Hypertrophic scar fibroblasts membrane‐hybridized cationic transfersomes enable efficient loading and transdermal delivery of TGF‐β1 siRNA through multiple skin penetration pathways. The biomimetic platform enhances homotypic targeting, transfection, and immune evasion, suppresses TGF‐β1‐driven fibrotic signaling, and reduces extracellular matrix ...
Hui Xing   +9 more
wiley   +1 more source

Versatile Microgel Platform for Intervertebral Disc Degeneration Therapy: Targeting Pericyte‐Mediated Fibrosis and Protecting Nucleus Pulposus Cells

open access: yesAdvanced Science, EarlyView.
The engineered MMS@TRP microgel enables targeted, acid‐responsive delivery of a miR‐21 inhibitor to pericytes. It effectively suppresses disc fibrosis by inhibiting TGF‐β signaling while protecting nucleus pulposus cells via sustained, antioxidant tannic acid release.
Fei Ma   +12 more
wiley   +1 more source

Influence of different frequencies of transcutaneous electrical nerve stimulation on the threshold and pain intensity in young subjects

open access: yesEinstein (São Paulo)
Objective To investigate the effects of different transcutaneous electrical nerve stimulation frequencies in nociception front of a pressure pain threshold and cold in healthy individuals. Methods Twenty healthy subjects were divided into four groups,
Adriana de Oliveira Gomes   +5 more
doaj   +1 more source

A Better Way to Decrease Knee Swelling in Patients with Knee Osteoarthritis: A Single-Blind Randomised Controlled Trial

open access: yesPain Research and Management, 2019
Objective. In this study, we compared the effects of intermittent pneumatic compression along with conventional treatment with cold-pack treatment along with conventional treatment on clinical outcomes in patients with knee osteoarthritis.
Zübeyir Sari   +4 more
doaj   +1 more source

Use of transcutaneous electrical acupoint stimulation for prevention of postoperative delirium in geriatric patients with silent lacunar infarction

open access: yes, 2019
Hai-Jun Hou, Fu-Shan Xue, Rui-Juan Guo Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, Beijing, People’s Republic of ChinaIn a preliminary study, Gao et al1 assessed the preventive effect of transcutaneous ...
Hou HJ, Xue FS, Guo RJ
core  

Extracellular Vesicle Packaged TDP43 Derived From ECs Exacerbates Cigarette Tar‐Related Atherosclerosis Progression via Enhancing Macrophage Extracellular Traps

open access: yesAdvanced Science, EarlyView.
Cigarette tar triggers EC‐derived EVs carrying TDP43, which binds VDAC1 to boost MAMs, mitochondrial Ca2+ overload, and METs formation in macrophages, accelerating smoking‐related AS progression, while retinoic acid binds TDP43 to block this pathogenic cascade.
Xinxin Zhu   +20 more
wiley   +1 more source

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