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BiomedicinesSpinal muscular atrophy (SMA) is an orphan disease characterized by the progressive degeneration of spinal alpha motor neurons. In recent years, nusinersen and several other drugs have been approved for the treatment of this disease.
Anton Novikov +7 more
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BiomedicinesBackground: Transcutaneous spinal stimulation (TSS) is a noninvasive stimulation approach to modulate spinal reflex circuit excitability after spinal cord injury (SCI) Posterior root muscle (PRM) reflexes can be used to characterize the change in excitability of spinal reflex circuits after TSS; these responses are likely influenced by stimulus ...
Evan B. Sandler +3 more
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Postural control in humans: a study using transcutaneous spinal cord stimulation
Experimental PhysiologyAbstract The aim of the study was to investigate the spinal mechanisms involved in regulating postural balance in humans. Participants stood in a normal stance, with their spinal postural networks either non‐invasively activated or not stimulated by electrical stimulation.
Natalia Shamantseva +5 more
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2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), 2023
A previous study by our group showed preliminary results showcasing the usage of optimal and individualized spinal cord transcutaneous stimulation (scTS) parameters during overground gait training to facilitate more repeatable gait kinematics profiles for one participant with an incomplete spinal cord injury (SCI). The goal of this study was to use the
Manan Anjaria +5 more
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A previous study by our group showed preliminary results showcasing the usage of optimal and individualized spinal cord transcutaneous stimulation (scTS) parameters during overground gait training to facilitate more repeatable gait kinematics profiles for one participant with an incomplete spinal cord injury (SCI). The goal of this study was to use the
Manan Anjaria +5 more
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Journal of Neurotrauma, 2020
Epidural spinal cord stimulation (SCS) is currently regarded as a breakthrough procedure for enabling movement after spinal cord injury (SCI), yet one of its original applications was for spinal spasticity. An emergent method that activates similar target neural structures non-invasively is transcutaneous SCS.
Ursula S, Hofstoetter +6 more
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Epidural spinal cord stimulation (SCS) is currently regarded as a breakthrough procedure for enabling movement after spinal cord injury (SCI), yet one of its original applications was for spinal spasticity. An emergent method that activates similar target neural structures non-invasively is transcutaneous SCS.
Ursula S, Hofstoetter +6 more
openaire +2 more sources
American Journal of Physiology-Heart and Circulatory Physiology, 2023
Individuals with spinal cord injury (SCI) have significant dysfunction in cardiovascular autonomic regulation. While recent findings postulate that spinal cord stimulation improves autonomic regulation, limited scope of past methods have tested only above level sympathetic activation, leaving significant uncertainty. To identify whether transcutaneous
Ryan, Solinsky +4 more
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Individuals with spinal cord injury (SCI) have significant dysfunction in cardiovascular autonomic regulation. While recent findings postulate that spinal cord stimulation improves autonomic regulation, limited scope of past methods have tested only above level sympathetic activation, leaving significant uncertainty. To identify whether transcutaneous
Ryan, Solinsky +4 more
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Rehabilitace a fyzikální lékařství
Introduction: Transcutaneous spinal cord stimulation (tSCS) is a non-invasive neuromodulation technique that provides a novel approach to the rehabilitation of individuals with spinal cord injury (SCI). Its goal is to increase the excitability of spinal circuits and facilitate residual neuronal connections that remain preserved, but are dysfunctional ...
Jiří Kříž +4 more
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Introduction: Transcutaneous spinal cord stimulation (tSCS) is a non-invasive neuromodulation technique that provides a novel approach to the rehabilitation of individuals with spinal cord injury (SCI). Its goal is to increase the excitability of spinal circuits and facilitate residual neuronal connections that remain preserved, but are dysfunctional ...
Jiří Kříž +4 more
openaire +1 more source
Automated Selectivity-Driven Algorithm for Transcutaneous Spinal Cord Stimulation
2025 International Conference On Rehabilitation Robotics (ICORR)Spinal cord injury (SCI) impairs motor function and quality of life. Transcutaneous Spinal Cord Stimulation (tSCS) is a non-invasive method to restore motor function by activating spinal circuits below the lesion. However, its effectiveness is limited by individual variability, reliance on manual electrode placement, and offline muscle analysis.
Mouhamed Zorkot +4 more
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Biomedical Engineering / Biomedizinische Technik, 2013
Non-patterned electrical spinal cord stimulation (SCS) via epidural electrodes can activate neural circuits involved in lower-limb motor control in individuals with spinal cord injury (SCI), and generate automatic, rhythmic flexion-extension movements in the paralyzed lower limbs.
U S, Hofstoetter +6 more
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Non-patterned electrical spinal cord stimulation (SCS) via epidural electrodes can activate neural circuits involved in lower-limb motor control in individuals with spinal cord injury (SCI), and generate automatic, rhythmic flexion-extension movements in the paralyzed lower limbs.
U S, Hofstoetter +6 more
openaire +2 more sources