Results 61 to 70 of about 25,608 (312)

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

Switching from Oral Cholinesterase Inhibitors to a Transdermal Donepezil Patch Attenuated Gastrointestinal Symptoms and Allowed Treatment Continuation in Three Patients with Alzheimer’s Disease in Clinical Settings

Brain Sciences
Background: Cholinesterase inhibitors (ChEIs) are commonly prescribed for the treatment of Alzheimer’s disease (AD) and achieve long-term benefits for cognition and survival in real-world settings.
Yumiko Motoi, Nobuo Sanjo
doaj   +1 more source

IIT-H team develops a novel drug delivery system [PDF]

, 2017
A team of researchers at the Indian Institute of Technology (IIT) Hyderabad have developed a novel drug-delivery system that releases a commonly used pain killer called diclofenac sodium at the target site in a controlled fashion such that there is ...
IIT, Hyderabad
core  

Transdermal iontophoresis patch with reverse electrodialysis [PDF]

Drug Delivery, 2017
Reverse electrodialysis (RED) technology generates energy from the salinity gradient by contacting waters with different salinity. Herein, we develop the disposable skin patch using this eco-friendly energy. The current density, which can be controlled easily without special circuit, is enough to iontophoretic drug delivery.
Joon Lee, Kilsung Kwon, Minyoung Kim, Joonhong Min, Nathaniel S. Hwang, Won-serk Kim   +5 more
openaire   +3 more sources

Epidermal Patch Technologies for Integrated Healthcare and Infection Management

Advanced Healthcare Materials, EarlyView.
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang, Atakan Tevlek, Pawel L. Urban, Boaz Mizrahi, Onome Ejeromedoghene, Roshan Deen, Yuanjing Lin, Jagan Mohan Dodda   +7 more
wiley   +1 more source

Digital Microneedles for Multiplexed Transdermal Sensing via Fluorescent QR Codes

Advanced Materials, EarlyView.
Digital fluorescent microneedles encode biochemical information in skin into scannable QR codes through threshold‐activated probes that generate binary on/off signals. By transforming analog fluorescence into discrete digital patterns, this platform enables calibration‐free, multiplexed transdermal sensing of physiologically relevant biomarkers ...
Farbod Abazar, Shahrokh Vahabi, Elena Bellotti, Martina Corsi, Irene Nocera, Paola Orlandi, Guido Bocci, Giuseppe Barillaro   +7 more
wiley   +1 more source

Comparison of transdermal diclofenac patch with oral diclofenac as an analgesic modality following multiple premolar extractions in orthodontic patients: A cross over efficacy trial

Contemporary Clinical Dentistry, 2010
Aims: This study was performed to compare the degree of post operative analgesia, patient compliance, and frequency of adverse events with the use of oral diclofenac tablets and transdermal diclofenac patch following multiple premolar extractions in ...
Hemant Bhaskar, Pranav Kapoor, Ragini
doaj   +1 more source

Treatment with subcutaneous and transdermal fentanyl: Results from a population pharmacokinetic study in cancer patients [PDF]

, 2016
Purpose: Transdermal fentanyl is effective for the treatment of moderate to severe cancer-related pain but is unsuitable for fast titration. In this setting, continuous subcutaneous fentanyl may be used.
Abrantes, J.A. (João), Bruijn, P.J. (Peter) de, Falcão, A. (Amílcar), Jönsson, S. (Siv), Kuip, E.J.M. (Evelien), Mathijssen, A.H.J. (Ron), Oosten, A.W. (Astrid), Rijt, C.C.D. (Carin) van der   +7 more
core   +1 more source

High‐Performance Transparent, Deformable, and Recoverable Biomimetic Stevia–PVA Hydrogel Triboelectric Nanogenerator with Machine Learning‐Assisted Motion Recognition

Advanced Materials, EarlyView.
A transparent, deformable stevia–PVA hydrogel triboelectric nanogenerator delivers significantly enhanced mechanical strength and electrical output through biomimetic hydrogen‐bonded networks. Coupled with machine learning–assisted signal recognition, the self‐powered hydrogel enables accurate human‐motion sensing for intelligent wearable and IoT ...
Thien Trung Luu, Bui Minh Quang, Toan Minh Pham, Jinsoo Kim, Kyungwho Choi, Dukhyun Choi   +5 more
wiley   +1 more source

Transdermal nitroglycerine enhances postoperative analgesia of intrathecal neostigmine following abdominal hysterectomies

Indian Journal of Anaesthesia, 2010
This study was carried out to assess the effect of nitroglycerine (transdermal) on intrathecal neostigmine with bupivacaine on postoperative analgesia and note the incidence of adverse effects, if any.
Fareed Ahmed, Ashish Garg, Vipul Chawla, Mamta Khandelwal   +3 more
doaj   +1 more source