Results 51 to 60 of about 612,532 (342)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Pressure transducer [PDF]

open access: yes, 1969
Pressure-sensitive transducer, consisting of a series of spindle-supported electrically conductive metal washers connected to electrical sensing circuitry, determines the force exerted between a mounting bolt and nut on relatively fragile ...
Baker, C. D.
core   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Neuronal activity in the ventral tegmental area during goal-directed navigation recorded by low-curvature microelectrode arrays

open access: yesMicrosystems & Nanoengineering
Navigating toward destinations with rewards is a common behavior among animals. The ventral tegmental area (VTA) has been shown to be responsible for reward coding and reward cue learning, and its response to other variables, such as kinematics, has also
Wei Xu   +14 more
doaj   +1 more source

Acoustical transducer calibrating system and apparatus [PDF]

open access: yes, 1973
An acoustical transducer calibrating system includes a differential pressure actuating device having an inner chamber for applying differential pressures to the transducer, and an outer chamber for vacuum sealing.
Cohn, R. B., Lewis, T. L.
core   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

Pressure transducer [PDF]

open access: yes, 1972
A pressure transducer is described in which the sensing element is a crystal of the monomeric charge transfer complex of pyrene and ...
Rembaum, A.
core   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Phototactic and Chemotactic Signal Transduction by Transmembrane Receptors and Transducers in Microorganisms

open access: yesSensors, 2010
Microorganisms show attractant and repellent responses to survive in the various environments in which they live. Those phototaxic (to light) and chemotaxic (to chemicals) responses are regulated by membrane-embedded receptors and transducers.
Daisuke Suzuki   +4 more
doaj   +1 more source

An All-Silicon Resonant Pressure Microsensor Based on Eutectic Bonding

open access: yesMicromachines, 2023
In this paper, an all-Si resonant pressure microsensor based on eutectic bonding was developed, which can eliminate thermal expansion coefficient mismatches and residual thermal stresses during the bonding process.
Siyuan Chen   +6 more
doaj   +1 more source

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