Results 41 to 50 of about 346,421 (355)
Digital manufacturing of personalised footwear with embedded sensors
Scientific Reports, 2023 The strong clinical demand for more accurate and personalized health monitoring technologies has called for the development of additively manufactured wearable devices.
Marco R. Binelli +8 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Intravascular forward-looking ultrasound transducers for microbubble-mediated sonothrombolysis
Scientific Reports, 2017 Effective removal or dissolution of large blood clots remains a challenge in clinical treatment of acute thrombo-occlusive diseases. Here we report the development of an intravascular microbubble-mediated sonothrombolysis device for improving ...
Jinwook Kim +6 more
semanticscholar +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
FEM-Based Design and Characterization of a Millimeter-Scale Piezoelectric Resonance Force Sensor
IEEE AccessThis paper presents a millimeter-scale piezoelectric effect-based force sensor that uses the change in its resonant frequency as the detection principle for high sensitivity and a wide measurement range.
Aoto Yamazaki +4 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Self-stabilizing three-dimensional particle manipulation via a single-transducer acoustic tweezer [PDF]
, 2023 Lu Shen +5 more
openalex +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Applied Sciences, 2019 Fouling accumulation in pipelines is a well-known problem in industry across various applications. The build-up of fouling within a pipe can reach a detrimental state, leading to pipe blockages that, in turn, result in pipe bursts. As pipelines transport
Habiba Lais +3 more
doaj +1 more source
Development of High-Speed On–Off Valves and Their Applications
Chinese Journal of Mechanical Engineering, 2022 With the widespread application of the computer and microelectronic technology in the industry, digitization becomes the inevitable developing trend of the hydraulic technology.
He Wang +4 more
doaj +1 more source