Results 51 to 60 of about 83,700 (269)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Advances in Random Fiber Lasers and Their Sensing Application
Sensors, 2020 Compared with conventional laser, random laser (RL) has no resonant cavity, reducing the requirement of cavity design. In recent years, the random fiber laser (RFL), a novel kind of RL, has made great progress in theories and experiments.
Hong Chen +9 more
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Theoretical Computer Science, 1986 The factor transducer of a word associates to each of its factors (or subwords) their first occurrence. Optimal bounds on the size of minimal factor transducers together with an algorithm for building them are given. Analogous results and a simple algorithm are given for the case of subsequential suffix transducers. Algorithms are applied to repetition
openaire +3 more sources
Transducers with Origin Information [PDF]
, 2014 Call a string-to-string transducer regular if it can be realised by one of the following equivalent models: mso transductions, two-way deterministic automata with output, and streaming transducers with registers. This paper proposes to treat origin information as part of the semantics of a regular string-to-string transducer.
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Visibly Pushdown Transducers [PDF]
, 2008 Visibly pushdown automata have been recently introduced by Alur and Madhusudan as a subclass of pushdown automata. This class enjoys nice properties such as closure under all Boolean operations and the decidability of language inclusion. Along the same line, we introduce here visibly pushdown transducers as a subclass of pushdown transducers.
Raskin, Jean-François +1 more
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Combined Attenuation and High-Resolution Fault Measurements Using Chaos-OTDR
IEEE Photonics Journal, 2015 We propose a combined attenuation and high-resolution fault measurement method using chaos optical time-domain reflectometry (OTDR). Utilizing the pulse-modulated chaotic light and correlation operation, this technique realizes fiber attenuation ...
Xiangyu Dong +6 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source