Results 261 to 270 of about 626,396 (286)
Some of the next articles are maybe not open access.
Genetic Approaches to Visual Transduction in Drosophila melanogaster
Receptors and Channels, 2003Because almost everything we know about Drosophila phototransduction has come from studies based on genetic approaches, this review begins with a discussion of genetic approaches. We then present a brief overview of Drosophila phototransduction (section on Drosophila phototransduction: an overview) followed by a more detailed treatment of individual ...
William L, Pak, Hung-Tat, Leung
openaire +2 more sources
Genetics of signal transduction: tales from the mouse
Current Opinion in Genetics & Development, 1994Recent progress in understanding signal transduction owes much to new genetic approaches, first by unraveling the molecular basis of classic mutations, and then by the use of gene targeting. Recent studies have examined mammalian signal transduction from cell surface to nucleus, especially ligand-receptor systems and cytosolic signal transducers.
A, Imamoto, P, Soriano, P L, Stein
openaire +2 more sources
MOLECULAR GENETICS OF SIGNAL TRANSDUCTION IN DICTYOSTELIUM
Annual Review of Biochemistry, 1996In conditions of starvation, the free living amoebae of Dictyostelium enter a developmental program: The cells aggregate by chemotaxis to form a multicellular structure that undergoes morphogenesis and cell-type differentiation. These processes are mediated by a family of cell surface CAMP receptors (CARS) that act on a specific heterotrimeric G ...
C A, Parent, P N, Devreotes
openaire +2 more sources
Genetic analyses of sweet taste transduction
Food Chemistry, 1997A genetic analysis of sweet taste transduction was initiated using fruitflies and humans. In flies, behavioral and receptor cell electrophysiology data indicate different mechanisms for fructose and glucose in or before the receptor cells. Fructose nontasters (FN) and glucose nontasters (GN) were selected from natural populations of adults and larvae ...
Linda M. Kennedy +3 more
openaire +1 more source
Genetic transduction in freshwater ecosystems
Freshwater Biology, 2007Summary1. Lateral genetic exchange is a profound consequence of the co‐existence of viruses (bacteriophages) and bacteria in freshwater ecosystems. Transduction is distinct from other mechanisms of genetic exchange because it is driven by potentially lethal agents external to the donor and recipient cells.
openaire +1 more source
Genetic and biochemical analysis of TGFβ signal transduction
Cytokine & Growth Factor Reviews, 1997TGF beta-like ligands are involved in many different developmental processes that pattern a variety of tissues in invertebrates and vertebrates. In the last few years, rapid progress has been made toward elucidating the developmental roles of the TGF beta-like pathways and identifying the novel components involved in transducing their signals ...
R W, Padgett, C, Savage, P, Das
openaire +2 more sources
Drosophila abl and genetic redundancy in signal transduction
Trends in Genetics, 1991Genetic studies on Drosophila Abl and, more recently, on mouse c-Abl and c-Src indicate that the functions of these non-receptor tyrosine kinases may duplicate activities of other molecules within signal transduction pathways. In Drosophila, second-site mutations have been recovered that disrupt the redundant functions so that the Abl tyrosine kinase ...
openaire +2 more sources
The promise of signal transduction in genetically driven sarcomas of the nerve
Experimental Neurology, 2018Neurofibromatosis type 1 (NF1) is an autosomal dominant tumor predisposition syndrome. Malignant peripheral nerve sheath tumors (MPNST) are aggressive soft tissue sarcomas arising from peripheral nerve sheaths, and the most commonly lethal feature associated with NF1.
AeRang Kim, Christine A. Pratilas
openaire +2 more sources
Molecular Genetics of Visual Transduction in Drosophila
1992We have taken a reverse genetics approach to study the molecular basis of phototransduction in Drosophila melanogaster. We have identified genes which are preferentially expressed in the compound eye of the fruitfly by subtractive hybridization. Among those eye-specific sequences we have characterized the ninaA gene, a gene encoding for a photoreceptor
B.-H. Shieh, C. S. Zuker
openaire +1 more source
Successful genetic transduction in vivo into synovium by means of electroporation
Biochemical and Biophysical Research Communications, 2002This present study aims at establishing a novel in vivo gene delivery system for intra-articular tissues. Plasmid DNA (pDNA) carrying the firefly luciferase or enhanced green fluorescent protein (EGFP) genes as markers was injected into a joint space and electric stimuli were given percutaneously with a pair of electrodes.
Suzuyo, Ohashi +9 more
openaire +2 more sources