Results 281 to 290 of about 3,488,111 (320)
Some of the next articles are maybe not open access.
Genetic transduction in freshwater ecosystems
Freshwater Biology, 2008Summary1. Lateral genetic exchange is a profound consequence of the co‐existence of viruses (bacteriophages) and bacteria in freshwater ecosystems. Transduction is distinct from other mechanisms of genetic exchange because it is driven by potentially lethal agents external to the donor and recipient cells.
O. Ogunseitan
semanticscholar +2 more sources
Genetic approaches to visual transduction in Drosophila melanogaster.
Receptors and Channels, 2003Because almost everything we know about Drosophila phototransduction has come from studies based on genetic approaches, this review begins with a discussion of genetic approaches. We then present a brief overview of Drosophila phototransduction (section on Drosophila phototransduction: an overview) followed by a more detailed treatment of individual ...
W. Pak, Hung‐Tat Leung
semanticscholar +3 more sources
Genetic approaches to mechanosensory transduction
Current Opinion in Neurobiology, 1995Genetic approaches in several organisms provide the means of solving a previously intractable problem: characterizing the molecular foundations of the mechanical senses. In nematode mechanosensory cells, members of a novel class of epithelial ion channel subunits have been implicated as components of a mechanically gated channel.
M, Kernan, C, Zuker
openaire +2 more sources
Genetics of signal transduction in invertebrates
Current Opinion in Genetics & Development, 1994Receptor tyrosine kinases regulate a number of different cell fate decisions during invertebrate development. Genetic analysis of the signal transduction pathways activated by these kinases suggests that they converge upon a common pathway involving Ras and a cascade of cytoplasmic kinases, diverging again in the nucleus with the regulation of specific
B, Dickson, E, Hafen
openaire +2 more sources
Chemical genetic analysis of signal transduction pathways
Expert Opinion on Therapeutic Targets, 2006Covalent modification of proteins by phosphorylation represents a major mechanism of signal transduction that contributes to many physiological and pathophysiological processes. The enzymes that regulate protein phosphorylation (e.g., protein kinases and phosphatases) are, therefore, potential targets for the rational design of small-molecule drugs for
Anja, Jaeschke, Roger J, Davis
openaire +2 more sources
Genetic analyses of sweet taste transduction
Food Chemistry, 1997A genetic analysis of sweet taste transduction was initiated using fruitflies and humans. In flies, behavioral and receptor cell electrophysiology data indicate different mechanisms for fructose and glucose in or before the receptor cells. Fructose nontasters (FN) and glucose nontasters (GN) were selected from natural populations of adults and larvae ...
Linda M. Kennedy +3 more
openaire +1 more source
Abiotic stress signal transduction in plants: Molecular and genetic perspectives.
Physiologia Plantarum, 2001Low temperature, drought and salinity are major adverse environmental factors that limit plant productivity. Understanding the mechanisms by which plants perceive and transduce these stress signals to initiate adaptive responses is essential for engineering stress‐tolerant crop plants.
L. Xiong, Jian‐Kang Zhu
semanticscholar +3 more sources
Angewandte Chemie, 2019
Programming cells to sense multiple-inputs and activate cellular signal transduction cascades is of great interest. Albeit it has been achieved via engineering of genetic circuits using synthetic biology tools, a nongenetic and generic approach remains ...
Shan Chen +6 more
semanticscholar +1 more source
Programming cells to sense multiple-inputs and activate cellular signal transduction cascades is of great interest. Albeit it has been achieved via engineering of genetic circuits using synthetic biology tools, a nongenetic and generic approach remains ...
Shan Chen +6 more
semanticscholar +1 more source
Genetics of signal transduction: tales from the mouse
Current Opinion in Genetics & Development, 1994Recent progress in understanding signal transduction owes much to new genetic approaches, first by unraveling the molecular basis of classic mutations, and then by the use of gene targeting. Recent studies have examined mammalian signal transduction from cell surface to nucleus, especially ligand-receptor systems and cytosolic signal transducers.
A, Imamoto, P, Soriano, P L, Stein
openaire +2 more sources
MOLECULAR GENETICS OF SIGNAL TRANSDUCTION IN DICTYOSTELIUM
Annual Review of Biochemistry, 1996In conditions of starvation, the free living amoebae of Dictyostelium enter a developmental program: The cells aggregate by chemotaxis to form a multicellular structure that undergoes morphogenesis and cell-type differentiation. These processes are mediated by a family of cell surface CAMP receptors (CARS) that act on a specific heterotrimeric G ...
C A, Parent, P N, Devreotes
openaire +2 more sources