Results 51 to 60 of about 13,171 (232)
The Journal of Dermatology, EarlyView.ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory dermatitis underpinned by Type 2 inflammation driven by cytokines such as IL‐4 and IL‐13. It is characterized by skin barrier dysfunction, Th2 immune deviation, and pruritus. While biologics and oral Janus kinase (JAK) inhibitors demonstrate high therapeutic efficacy by targeting cytokines that ...
Gaku Tsuji +7 more
wiley +1 more source
Is There a Relationship between Transepidermal Water Loss and Microbial Biodiversity on the Skin?
Cosmetics, 2019 As described in previous work, TEWL (transepidermal water loss) is used as an indicator of skin barrier function and health by scientists at top research institutions.
Christopher Wallen-Russell
doaj +1 more source
Medicinal potential of Panax ginseng and its ginsenosides in atopic dermatitis treatment
Journal of Ginseng Research, 2020 Atopic dermatitis (AD) is a chronic and relapsing inflammatory disease that affects 1%–20% of people worldwide. Despite affecting many people, AD current treatments, such as corticosteroids and calcineurin inhibitors, have not only harmful secondary ...
Laura Rojas Lorz +2 more
doaj +1 more source
Evaluation und Standardisierung von Hauttestungen zur Diagnostik der irritativen Kontaktdermatitis [PDF]
, 2004 Ziel der vorliegenden Arbeit ist es, durch Variation verschiedener Applikationszeiten, Konzentrationen und Vorbehandlungen (VB) der Teststellen zu evaluieren, ob der bisher übliche 24-stündige epikutane Irritationstest auf 4 Stunden ...
Effendy, Isaak (Prof. Dr.) +1 more
core +1 more source
Allergy, EarlyView.ABSTRACT Atopic dermatitis and psoriasis are two common cutaneous chronic inflammatory diseases. Although they share similar immunological mechanisms, their clinical implications in the patient are different. This review compares both diseases from different points of view such as genetics, natural history, triggers of disease, and skin barrier defects
Tali Czarnowicki +6 more
wiley +1 more source
Skin barrier function in children with eosinophilic esophagitis
Journal of Allergy and Clinical Immunology: GlobalBackground: Eosinophilic esophagitis (EoE) is associated with epithelial barrier dysfunction of the esophagus. Studies suggest that the skin lipidomic profile is altered in EoE; therefore, we hypothesized that skin barrier function would be compromised ...
Blake Civello, BS +8 more
doaj +1 more source
Health Science Reports, 2023 Background and Aims Female pattern hair loss affects females of all ages with a trend to increase after menopause. This disorder may have significant psychological impact and lead to anxiety and depression.
Carr Cai +6 more
doaj +1 more source
Turkderm Turkish Archives of Dermatology and Venereology, 2023 Background and Design: Skin barrier function in patients with breast cancer-related lymphedema (BCRL) has rarely been evaluated. This study aimed to investigate transepidermal water loss (TEWL), stratum corneum hydration (SCH), and sebum level (SL) on ...
Münevver Güven +4 more
doaj +1 more source
Rapid Human Skin Barrier Disruption by Sodium Dodecyl Sulfate and Associated Molecular Mechanisms
Allergy, EarlyView.Short‐term exposure to SDS rapidly disrupts human skin barrier integrity within minutes, as detected by real‐time electrical impedance spectroscopy. SDS‐induced barrier dysfunction is driven by oxidative stress, leading to suppression of immune/barrier mediators and activation of stress, lipid remodeling, and epidermal differentiation pathways ...
Manru Li +10 more
wiley +1 more source
Assessing the sensitivity of two TEWL measuring methods: open vs. closed chamber [PDF]
, 2015 Transepidermal water loss (TEWL) is a key parameter in the assessment of skin barrier impairment and recovery. The aim of this study was to perform a comparative assessment of the two types of TEWL instruments, with specific emphasis on their sensitivity
Chan, Melissa +4 more
core