Results 81 to 90 of about 12,814 (238)

Prevention of Atopic Dermatitis in High‐Risk Infants: A Review of the Role of Lipid‐Based Barrier Repair Therapy

Pediatric Dermatology, EarlyView.
ABSTRACT Background/Objective Growing evidence highlights the role of physiological lipids, namely ceramides, cholesterol, and free fatty acids, in maintaining skin barrier function and preventing atopic dermatitis (AD). Current evidence on the efficacy, safety, and clinical relevance of stratum corneum (SC) lipid‐based therapies to prevent AD and ...
Chon‐Wai Jeremy Chan, Marty O. Visscher   +1 more
wiley   +1 more source

Midface volumization and skin quality enhancement with a hyaluronic acid–polynucleotide hybrid filler: a 24-week prospective open-label study

Journal of Dermatological Treatment
Background Facial aging is characterized by midface volume loss from structural and dermal atrophy.Objectives To evaluate the efficacy and safety of a hyaluronic acid–polynucleotide (HA–PN) hybrid filler for temporary restoration of anteromedial cheek ...
So Young Lee, Choon Shik Youn, Kui Young Park   +2 more
doaj   +1 more source

Scientific Opinion on the substantiation of a health claim related to Wheat Polar Lipid Extract and protection of the skin against dehydration pursuant to Article 13(5) of Regulation (EC) No 1924/2006 [PDF]

, 2012
<p>Following an application from Extraction Purification Innovation France, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of France, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was
EFSA Panel on Dietetic Products, Nutrition and Allergies
core   +1 more source

Dupilumab Reduces Pruritus in Twins With Sjögren–Larsson Syndrome

Pediatric Dermatology, EarlyView.
ABSTRACT Sjögren–Larsson Syndrome (SLS), now termed ALDH3A2‐syndromic epidermal differentiation disorder (sEDD), is a rare genetic disorder marked by thickened skin, spasticity, and intellectual disability. Intractable pruritus is a nearly universal and debilitating feature of SLS that remains poorly managed by current therapies. We describe 4‐year‐old
Kennedy Gallagher, Rame Yousif, Kathryn Hummel, Amy S. Paller   +3 more
wiley   +1 more source

Altered Prostasin (CAP1/Prss8) Expression Favors Inflammation and Tissue Remodeling in DSS-induced Colitis. [PDF]

, 2016
Inflammatory bowel diseases (IBD) including ulcerative colitis and Crohn's disease are diseases with impaired epithelial barrier function. We aimed to investigate whether mutated prostasin and thus, reduced colonic epithelial sodium channel activity ...
Auberson, M., Bonny, O., Hummler, E., Keppner, A., Malsure, S., Nobile, A.   +5 more
core   +1 more source

A Novel Topical Emollient Plus for Canine Atopic Dermatitis: A Clinical Trial Assessing Efficacy and User Acceptance

Veterinary Dermatology, EarlyView.
Background: Canine atopic dermatitis (cAD) is a common, chronic skin condition characterised by epidermal barrier dysfunction, immune dysregulation and cutaneous dysbiosis. While “emollient plus” formulations are widely used in human atopic dermatitis, their role in cAD remains underexplored. Hypothesis/Objectives: To evaluate the clinical efficacy and
Beatriz Fernandes, António Caldeira Mendes, Susana Paula Alves, Vanessa Schmidt, Ana Filipa Bizarro, Marta Pinto, Hugo Pereira, Joana Marto, Ana Mafalda Lourenço   +8 more
wiley   +1 more source

Facial application of high-concentration carbon dioxide prevents epidermal impairment associated with environmental changes

Clinical, Cosmetic and Investigational Dermatology, 2019
Katsuyuki Yuki, Sawako Kawano, Shinobu Mori, Takatoshi Murase Biological Science Laboratories, Kao Corporation, Ichikai-machi, Haga-gun, Tochigi, Japan Purpose: The transdermal application of carbon dioxide (CO2) gas dissolved in a solution and bathing ...
Yuki K, Kawano S, Mori S, Murase T
doaj  

Predicting Skin Permeability by means of Computational Approaches : Reliability and Caveats in Pharmaceutical Studies [PDF]

, 2019
© 2019 American Chemical Society.The skin is the main barrier between the internal body environment and the external one. The characteristics of this barrier and its properties are able to modify and affect drug delivery and chemical toxicity parameters.
Almerico, Anna Maria, Hoffman, Ewelina, Hutter, Victoria, Pecoraro, Beatrice, Traynor, Matthew, Tutone, Marco   +5 more
core   +2 more sources

Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight

Experimental Physiology, EarlyView.
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley   +1 more source

Advanced Characterization of Imiquimod-Induced Psoriasis-Like Mouse Model

Pharmaceutics, 2020
Many autoimmune disorders such as psoriasis lead to the alteration of skin components which generally manifests as unwanted topical symptoms. One of the most widely approved psoriasis-like animal models is the imiquimod (IMQ)-induced mouse model.
Mehwish Jabeen, Anne-Sophie Boisgard, Alix Danoy, Naima El Kholti, Jean-Paul Salvi, Roselyne Boulieu, Bérengère Fromy, Bernard Verrier, Myriam Lamrayah   +8 more
doaj   +1 more source