Results 191 to 200 of about 851,785 (340)

Rapid expression of therapeutic antibodies in mammalian cells via mRNA transfection. [PDF]

MAbs
Chavalparit T, Barry C, Gunter H, Gillard M, Mercer T, Marcellin E.   +5 more
europepmc   +1 more source

In vivo Testis Transfection Efficiently Produced Transfected Sperm Cells in Ram but not Rooster [PDF]

, 2020
A. Ebnali, A. Dehghani Poudeh, Akbar Pirestani, Mohsen Forouzanfar, Shahin Eghbalsaied   +4 more
openalex  

Enhancing Magnetic Hyperthermia at the Cell Membrane by Anchoring 92R‐Functionalized Magnetic Nanoparticles to Low‐Endocytic CCR9 Surface Receptors

Advanced Healthcare Materials, EarlyView.
We present a strategy to enhance magnetic hyperthermia therapy by modulating nanoparticle–cell interactions. Antibody‐functionalized magnetic nanoparticles targeting the low‐internalizing CCR9 receptor enable spatially controlled membrane anchoring, reducing aggregation and maximizing heat generation under alternating magnetic fields.
David Egea‐Benavente, Isabel Corraliza‐Gorjón, Thomas S. van Zanten, María del Puerto Morales, Leonor Kremer, Domingo F. Barber   +5 more
wiley   +1 more source

EDAC-mediated O-acylisourea rearrangement for tertiary amine cationization of hyaluronic acid (HA) and its application as structural backbones in virus-inspired polyplexes. [PDF]

Bioact Mater
Li Y, Yao L, Liu J, Situ Y, Zhao C, Mao T, Wang X, Song R, Tai H, He Z, Lyu J, Wang W.   +11 more
europepmc   +1 more source

Inner-ear delivery of AAV2-retro robustly labels lateral olivocochlear efferents but results in off-target transfection in the contralateral cochlea and the brain

Mahmoud Khalil, Mikayla Bisignani, Karl Kandler   +2 more
openalex   +1 more source

Targeted Transfection Using PEGylated Cationic Liposomes Directed Towards P-Selectin Increases siRNA Delivery into Activated Endothelial Cells [PDF]

, 2019
Cristina Ana Constantinescu, Elena Valeria Fuior, Daniela Rebleanu, Mariana Deleanu, Viorel Simion, Geanina Voicu, Virginie Escriou, Ileana Mânduțeanu, Maya Simionescu, Manuela Călin   +9 more
openalex   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Transfection of the free-living alga Chromera velia enables direct comparisons with its parasitic apicomplexan relative, Toxoplasma gondii. [PDF]

J Cell Sci
Tengganu IF, Hu K.
europepmc   +1 more source

Stable transfection of Epstein-Barr virus (EBV) nuclear antigen 2 in lymphoma cells containing the EBV P3HR1 genome induces expression of B-cell activation molecules CD21 and CD23 [PDF]

, 1990
M. Cordier, Alain Calender, Marc Billaud, Ursula Zimber, Germain Rousselet, Oleg Pavlish, Jacques Banchereau, Thomas Tursz, G. W. Bornkamm, Gilbert Lenoir   +9 more
openalex   +1 more source

Photosensitizing Lipid Nanoparticles for Ferroptosis‐Enhanced Photodynamic Cancer Therapy via GPX4 Silencing

Advanced Healthcare Materials, EarlyView.
Photosensitizing lipid nanoparticles (PLNPs) are engineered by incorporating cholesterol–PEG–pheophorbide a into MC3‐based LNPs and encapsulating GPX4‐targeting siRNA. Upon light activation, PLNPs generate reactive oxygen species (ROS) while silencing GPX4 to induce ferroptosis.
Ga‐Hyun Bae, Seungyong Shin, Joo Dong Park, Eun‐Young Koh, Seunghyo Ko, Jieun Han, Chun Gown Park, Dong‐Hyun Kim, Kun Na, Wooram Park   +9 more
wiley   +1 more source