Results 201 to 210 of about 570,469 (297)

Artificial Intelligence‐Driven Nanoarchitectonics for Smart Targeted Drug Delivery

open access: yesAdvanced Materials, EarlyView.
This perspective introduces an artificial intelligence (AI)‐driven nanoarchitectonics framework for targeted drug delivery, combining database‐guided nanocarrier design, machine learning (ML)‐assisted surface engineering with a designed targeting system, and in silico modeling for dynamic optimization.
Hayeon Bae   +6 more
wiley   +1 more source

Cloned DHBV DNA transfection in vivo.

open access: bronze, 1988
Kazuhiko Hosoda   +5 more
openalex   +2 more sources

Synthesis of Tertiary Amine Assisted Cytocompatible Zn‐MOFs for Efficient Nucleic Acid Encapsulation and Delivery to Prostate Cancer Cells

open access: yesAdvanced Materials Interfaces, EarlyView.
The study explores the influence of a tertiary amine in loading genetic material in a hybrid composite. The study highlights how structural attributes and chemical composition govern the crystallinity and cytocompatibility of ZIF‐biocomposites that effectively deliver nucleic acid to cancer cells.
Shakil Ahmed Polash   +3 more
wiley   +1 more source

An Injection‐Molded Modified Silicone Rubber for Cancer‐on‐Chip Applications

open access: yesAdvanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This study describes the characterization and application of an injection‐molded functionalized PDMS fluidic insert for the commercially available Micronit system. Modified PDMS can accommodate cell culture and is able to covalently bind proteins for long‐lasting coatings under flow‐conditions.
Ben J. Haspels   +7 more
wiley   +1 more source

Hydroxychloroquine-Derived Ionizable Lipid Facilitates Spleen-Tropic Transfection and Enhances Cancer Immunotherapy. [PDF]

open access: yesChem Bio Eng
Fan J   +10 more
europepmc   +1 more source

Genetic Engineering Methods in Primary T Cells

open access: yesAdvanced Therapeutics, EarlyView.
Primary T cells can be engineered to confer them with novel therapeutic functions, allowing them to treat a variety of conditions. Genetic engineering can be either stable or transient, aiming to either express or inhibit a target gene. This review discusses the various genetic engineering tools available as well as their characteristics and ...
Anthony Youssef, Hui‐Shan Li
wiley   +1 more source

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