Results 201 to 210 of about 928,471 (414)
Transfection of Leishmania enriettii and expression of chloramphenicol acetyltransferase gene. [PDF]
, 1989 Avraham Laban, Dyann F. Wirth
openalex +1 more source
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo +11 more
wiley +1 more source
T14diLys/DOPE Liposomes: An Innovative Option for siRNA-Based Gene Knockdown?
PharmaceuticsBackground/Objectives: Bringing small interfering RNA (siRNA) into the cell cytosol to achieve specific gene silencing is an attractive but also very challenging option for improved therapies.
Sophie Meinhard +6 more
doaj +1 more source
Rapid and highly efficient mammalian cell engineering via Cas9 protein transfection.
Journal of Biotechnology, 2015 Xiquan Liang +11 more
semanticscholar +1 more source
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
Advanced Healthcare Materials, EarlyView.The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq +4 more
wiley +1 more source
The rat albumin gene promoter is appropriately regulated in transient but not in stable transfections [PDF]
, 1988 Robert Berland, Lawrence A. Chasin
openalex +1 more source
Secondary Transient Transfection of Stably Transfected Endothelial Cells [PDF]
BioTechniques, 2000 Reza Forough, James R. Hawker
openaire +4 more sources
Advanced Healthcare Materials, EarlyView.A dual‐functional hafnium oxide nanoplatform is developed for enhanced cancer radiotherapy. This innovative system combines the inherent radiosensitizing properties of high‐Z hafnium oxide with Bcl‐2 gene‐silencing capabilities. The nanoplatform demonstrated synergistic enhancement of radiotherapy efficacy through increased generation of reactive ...
Seungyong Shin +12 more
wiley +1 more source
Production of Living Nanoparticles for Blood Cancer Therapy [PDF]
, 2018 Current cancer therapies leave much to be desired because they are very harmful to the patient and cause a significant decrease in quality of life. Chimeric Antigen Receptors (CAR) are a promising novel approach for treating specific types of leukemia ...
Mitchell, Peter +2 more
core +1 more source
Advanced Healthcare Materials, EarlyView.This study developed 3D‐printable THA‐Col microgels for delivering BMP‐7 cmRNA. The key result is that hMSCs transfected on the biomaterials showed BMP‐7 secretion levels comparable to pre‐transfected hMSCs, therefore introducing a cmRNA‐activated matrix to promote bone healing.
Daphne van der Heide +7 more
wiley +1 more source