Results 81 to 90 of about 314,467 (275)
Entropy, 2018 The heat and matter transfer during glucose catabolism in living systems and their relation with entropy production are a challenging subject of the classical thermodynamics applied to biology.
Roberto Zivieri, Nicola Pacini
doaj +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
A mathematical model for entropy generation in a Powell-Eyring nanofluid flow in a porous channel
Heliyon, 2019 The continuous generation of entropy leads to exergy destruction which reduces the performance of a physical system. Hence, entropy minimization becomes necessary.
Hammed Abiodun Ogunseye +1 more
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Zhileng xuebao, 2014 In terms of direct-contact heat transfer process between cold air bubbles and immiscible liquid, the convection heat transfer equation was established and solved numerically.
Wang Wei, Zhang Xuejun, Jiang Min
doaj
Entropy Generation in MHD Flow of a Uniformly Stretched Vertical Permeable Surface under Oscillatory Suction Velocity [PDF]
, 2009 This paper reports the analytical calculation of the entropy generation due to heat and mass transfer and fluid friction in steady state of a uniformly stretched vertical permeable surface with heat and mass diffusive walls, by solving analytically the ...
Adesanya, A.O., Okedoye, A.M.
core
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Journal of Applied Fluid Mechanics, 2018 In this study the 2D laminar and steady water-based Al2O3 nanofluid flow over a cylinder with circular, horizontal and vertical elliptical cross section by constant surface temperature boundary condition has been studied.
K. Khajeh +3 more
doaj
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source