Results 131 to 140 of about 8,378,733 (308)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Linear decomposition of the optical transfer function for annular pupils

open access: yes, 2017
A technique for decomposing the Optical Transfer Function (OTF) into a novel set of basis functions has been developed. The decomposition provides insight into the performance of optical systems containing both wavefront error and apodization, as well as
Jim Schwiegerling, Schwiegerling, Jim
core   +1 more source

Binarization of Metaheuristics: Is the Transfer Function Really Important? [PDF]

open access: yesBiomimetics (Basel), 2023
Lemus-Romani J   +4 more
europepmc   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Description of boiling project burnout detector

open access: yes, 1957
Introduction: In order to effectively utilize the high heat flux available through the mechanism of nucleate boiling in forced convection heat transfer, it is of primary importance that the maximum flux or "burnout" conditions be known for the liquid ...
Reynolds John Mitchell, Raymond, M. W.
core  

DAPL project

open access: yes
DAPL Project □Kb j "-aCj. I ^ V*1 'btUl^ s™ North.DakSia ^fOflyctl eg; ^ .WOOUI , -©- ^nrl .^•'i «“■ nt Ptrt'.T; WJICTRMt South Dakota t-) '>..^.Ojy__ i„auV,« iM«t-«».
Energy Transfer Company;
core   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Diatom based transfer function for estimating the chemical composition of fossil water. Calibration based on salt lakes of the Lipez area in the southwestern Bolivian Altiplano.

open access: yesCarnets de Géologie, 2002
Diatom assemblages and water chemistry were studied in 13 shallow salt lakes in the southern part of the Bolivian Altiplano. At each locality bottom sediment and water samples were collected simultaneously.
Roux Maurice   +2 more
doaj  

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

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