Results 231 to 240 of about 17,526,649 (388)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Continuous wavelet based transfer function analysis of cerebral autoregulation dynamics for neuromonitoring using near-infrared spectroscopy. [PDF]

open access: yesFront Physiol
Thudium M   +12 more
europepmc   +1 more source

Transfer function analysis of dynamic cerebral autoregulation: A CARNet white paper 2022 update. [PDF]

open access: yesJ Cereb Blood Flow Metab, 2023
Panerai RB   +18 more
europepmc   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Model-agnostic neural mean field with a data-driven transfer function. [PDF]

open access: yesNeuromorphic Comput Eng
Spaeth A, Haussler D, Teodorescu M.
europepmc   +1 more source

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