Results 101 to 110 of about 28,533,667 (307)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Tax and transfer incidence in Australia [PDF]

open access: yes, 2015
This paper sheds light on how Australia\u27s tax and transfer system functions to distribute income across the population and over lifetimes. It: provides a descriptive analysis of the flow of major taxes (personal income tax and GST) and transfers ...
Productivity Commission
core  

Employment of the Factor Analysis Approach to Predict the Transfer Function Models [PDF]

open access: yesالمجلة العراقية للعلوم الاحصائية, 2012
المسألة التي يتناولها هذا البحث هي توظيف التحليل العاملي لبناء نماذج دالة التحويل ومن ثم التنبؤ, بالاعتماد على طريقة المكونات الرئيسة، وتطبيق ذلك على البيانات المناخية (درجة الحرارة وسرعة الرياح والإشعاع الشمسي والرطوبة النسبية) الخاصة بظاهرة التبخر ...
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Recovery from a transfer disruption

open access: yes, 2014
The present study examined the role of skill acquisition and skill transfer in relation to both Anderson's (1993) Adaptive Control of Thought theory and Logan's (1988) instance theory.
., Craig P. Speelman   +1 more
core   +1 more source

Application of transfer matrix and transfer function analysis to grating-type dielectric laser accelerators: Ponderomotive focusing of electrons

open access: yesPhysical Review Accelerators and Beams, 2017
The question of suitability of transfer matrix description of electrons traversing grating-type dielectric laser acceleration (DLA) structures is addressed.
Andrzej Szczepkowicz
doaj   +1 more source

Transfer function analysis of dynamic cerebral autoregulation: A CARNet white paper 2022 update. [PDF]

open access: yesJ Cereb Blood Flow Metab, 2023
Panerai RB   +18 more
europepmc   +1 more source

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