Results 41 to 50 of about 8,555 (214)
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
MATEC Web of Conferences, 2019 Extensive numerical study on the heat transfer performance of the gaseous nitrogen (GN) thermoregulation shroud surface was conducted in this work.
Ying Zhou, Chao He, Bai Bing, Ning Juan
doaj +1 more source
Length of transfer time between connecting trains – is there an ideal value?
Acta Polytechnica CTU Proceedings, 2023 Quality public transport is an essential part of global mobility. In general, there is an effort to ensure that as many transport users as possible use public transport. The public transport subsystems also include rail transport. Nowadays, traveling by
Jan Froněk +2 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Numerical Analysis on Effect of Geometric Parameter on Steam Condensation in Presence of Air
Yuanzineng kexue jishu, 2022 Steam condensation in the presence of air is an important thermal-hydraulic phenomenon in containment under loss of coolant accidents (LOCAs) or main steam line break accidents (MSLBs).
XIAO Jiayu;SUN Zhongning;LI Rongji;LI Wentao;DING Ming;CAO Xiaxin;BIAN Haozhi
doaj
Full-length dystrophin gene transfer to the mdx mouse in utero [PDF]
Gene Therapy, 2008 In utero gene therapy for genetic diseases, such as muscular dystrophies, offers potential advantages over postnatal treatment including vector delivery at the earliest point in the disease and treatment prior to full maturation of the immune system. This study examines in utero gene delivery of full-length murine dystrophin to the murine mdx model for
D P, Reay +8 more
openaire +2 more sources
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Performance analysis of shell and tube heat exchanger: Parametric study
Case Studies in Thermal Engineering, 2018 Enhancement of heat transfer through shell and tube exchangers stills taking high attention by researchers. The present work investigated the effect of shell diameter and tube length on heat transfer coefficient and pressure drop for shell side with both
Ammar Ali Abd +2 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Glucosylceramide acyl chain length is sensed by the glycolipid transfer protein.
PLoS ONE, 2018 The glycolipid transfer protein, GLTP, can be found in the cytoplasm, and it has a FFAT-like motif (two phenylalanines in an acidic tract) that targets it to the endoplasmic reticulum (ER).
Anders P E Backman +5 more
doaj +1 more source