Results 51 to 60 of about 8,555 (214)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Effects of Hydrophobic-Spot Periphery and Subcooling on Nucleate Pool Boiling from a Mixed-Wettability Surface

Journal of Thermal Science and Technology, 2013
The effect of subcooling and length of hydrophobic-spot periphery on nucleate pool boiling heat transfer from TiO2-coated surface with and without PTFE (polyetatafluoroethylene) hydrophobic circle spots at intermediate heat flux has been examined.
Bambang Joko SUROTO, Masahiro TASHIRO, Sana HIRABAYASHI, Sumitomo HIDAKA, Masamichi KOHNO, Yasuyuki TAKATA   +5 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

ĐIỀU CHỈNH PHÁP LUẬT THUẾ CHỐNG CHUYÊN GIA CỦA TRUNG QUỐC ĐỐI VỚI CÁC CÔNG TY ĐA QUỐC GIA

Tạp chí Khoa học Đại học Cần Thơ, 2004
Chinais one of the largest recipients of foreign investment capital in recent years.  Particularly in the year 2003,Chinais the largest recipient of foreign investment capital in the world with total capital of US$ 52 billion.  Foreign investment capital
Nguyễn Tấn Phát
doaj  

The relationship between preoperative relative second metatarsal length and postoperative transfer metatarsalgia following hallux valgus surgery

Acta Orthopaedica et Traumatologica Turcica
Objective: This study aimed to investigate the potential association between transfer metatarsalgia, a complication that may arise post operatively following hallux valgus surgery, and the preoperative relative second metatarsal length measured on ...
Bekir Karagoz, Hunkar Cagdas Bayrak, Durmuş Ekin Dincer   +2 more
doaj   +1 more source

Theoretical Evidence for the Distance-Dependent Photoinduced Electron Transfer of Porphyrin-Oligothiophene-Fullerene Triads

International Journal of Photoenergy, 2012
The ground and excited state properties of nT-C60 dyads and Por-nT-C60 triads (n=4, 8, and 12) have been theoretically investigated by using the time-dependent density functional theory together with a set of extensive multidimensional visualization ...
Shan Zhang, Yuanzuo Li, Jing Liu, Meiyu Zhao, Yueyi Han, Yong Ding, Peng Song, Fengcai Ma   +7 more
doaj   +1 more source

On the Thermo-flow Behavior of a Wall Jet with an Oscillating Segment over a Backward-facing Step [PDF]

Journal of Applied Fluid Mechanics
We numerically investigate fluid–structure interaction (FSI) in a forced-convection wall-jet flow over a backward-facing step, considering various airflow and elastic-segment parameters. The flow is incompressible and laminar ( ). Downstream of the step,
R. Neishapouri, S. E. Razavi, M. Jafari
doaj   +1 more source