Transfer RNA-derived fragment production in calves challenged with Mycoplasma bovis or co-infected with bovine viral diarrhea virus and Mycoplasma bovis in several tissues and blood [PDF]
Frontiers in Veterinary ScienceUnderstanding the molecular mechanisms underlying immune response can allow informed decisions in drug or vaccine development, and aid in the identification of biomarkers to predict exposure or evaluate treatment efficacy. The objective of this study was
Anna K. Goldkamp +5 more
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Transfer RNA-derived fragment tRF-36 modulates varicose vein progression via human vascular smooth muscle cell Notch signaling [PDF]
Open Life SciencesVaricose veins are a prevalent vascular disorder affecting millions of individuals worldwide, and we previously reported transfer RNA-derived fragment (tRF) involvement in varicose veins.
Chen Guojun +4 more
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tRFtarget: a database for transfer RNA-derived fragment targets [PDF]
Nucleic Acids Research, 2021 Lingeng Lu, Zuoheng Wang, Ningshan Li
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Clinical diagnostic values of transfer RNA-derived fragment tRF-19-3L7L73JD and its effects on the growth of gastric cancer cells [PDF]
Journal of Cancer, 2021 Yongfu Shao, Junming Guo, Xiuchong Yu
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Transfer RNA‐derived fragment 5′tRF‐Gly promotes the development of hepatocellular carcinoma by direct targeting of carcinoembryonic antigen‐related cell adhesion molecule 1 [PDF]
Cancer Science, 2022 Weilin Wang
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Transfer RNA derived fragment, tRF-Glu-CTC, aggravates the development of neovascular age-related macular degeneration [PDF]
TheranosticsMeidong Zhu, Zhang Yihan
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The abundance of a transfer RNA-derived RNA fragment small RNA subpopulation is enriched in cauda spermatozoa [PDF]
ExRNA, 2020 The small RNA (sRNA) landscape of mammalian spermatozoa is considerably altered as these gametic cells migrate through the segment specific microenvironments of the epididymis.
Simone J. Stanger +6 more
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A tRNA-derived fragment from Chinese yew suppresses ovarian cancer growth via targeting TRPA1
Molecular Therapy: Nucleic Acids, 2022 Drug discovery from plants usually focuses on small molecules rather than such biological macromolecules as RNAs. Although plant transfer RNA (tRNA)-derived fragment (tRF) has been associated with the developmental and defense mechanisms in plants, its ...
Kai-Yue Cao +9 more
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BMC Women's Health, 2022 Background The diagnosis of endometriosis (EMs) is still based on laparoscopic observation. This study tries to verify whether exosomal tRNA-derived fragments (tRFs) in leucorrhea can be used as non-invasive diagnostic markers.
Yingxue Li +6 more
doaj +1 more source
Journal of Translational Medicine, 2023 Background Myopia has emerged as a major public health concern globally, which is tightly associated with scleral extracellular matrix (ECM) remodeling and choroidal vasculopathy. Choroidal vasculopathy has gradually been recognized as a critical trigger
Chang Liu +7 more
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