Results 51 to 60 of about 113,035 (190)
tRF-1001: A potential therapeutic target for ocular neovascular diseases
Molecular Therapy: Nucleic Acids, 2023 Pradeep Reddy Cingaram
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TsRNA-49-73-Glu-CTC: A promising serum biomarker in non-small cell lung cancer.
PLoS ONEObjectiveLung cancer has the highest incidence and mortality rates globally, with the majority of cases classified as non-small cell lung cancer (NSCLC). Due to the absence of specific tumor biomarkers, most lung cancer cases are diagnosed at an advanced
Chenyu Li +3 more
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Assembly and analysis of the complete mitochondrial genome of endangered plant Tilia amurensis Rupr
Frontiers in Plant ScienceIntroductionTilia amurensis Rupr., a deciduous tree of the genus Tilia in the Malvaceae family, is classified as a second-class key protected wild plant in China. This study aimed to sequence and analyze the complete mitochondrial genome of T.
Xiao Liu +8 more
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Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Advanced Functional Materials, EarlyView.A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo +7 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.The collagen nanofiber (CNF) gel supports cancer cell culture, exhibiting cell morphology and cancer‐related protein expression similar to Matrigel. It offers a higher collagen concentration than commercial gels. Additionally, the CNF gel allows replication of the high elasticity of in vivo cancer tissue by controlling collagen fiber sizes, ranging ...
Naoko Sasaki +4 more
wiley +1 more source
Serum transfer RNA-derived fragment tRF-31-79MP9P9NH57SD acts as a novel diagnostic biomarker for non-small cell lung cancer. [PDF]
J Clin Lab Anal, 2022 Li J, Cao C, Fang L, Yu W.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj +23 more
wiley +1 more source
Expression, functional role, and mechanistic insights into tRF-His-GTG-008 in lung adenocarcinoma
World Journal of Surgical OncologyObjective Transfer RNA-derived fragments (tRFs) represent a class of non-coding RNAs, typically ranging from 16 to 40 nucleotides in length, and have been implicated in the regulation of oncogenic processes. Despite emerging evidence of their involvement
Lilin Luo +7 more
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Advanced Healthcare Materials, EarlyView.This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang +17 more
wiley +1 more source