Results 91 to 100 of about 4,527,665 (350)

T7 RNA polymerase‐driven inducible cell lysis for DNA transfer from Escherichia coli to Bacillus subtilis

open access: yesMicrobial Biotechnology, 2017
Summary The majority of the good DNA editing techniques have been developed in Escherichia coli; however, Bacillus subtilis is better host for a plethora of synthetic biology and biotechnology applications. Reliable and efficient systems for the transfer
Mario Juhas, James W. Ajioka
doaj   +1 more source

Complete chloroplast genome sequence of Chrysosplenium macrophyllum and Chrysosplenium flagelliferum (Saxifragaceae)

open access: yesMitochondrial DNA. Part B. Resources, 2020
The complete chloroplast genome of Chrysosplenium macrophyllum Oliv. and Chrysosplenium flagelliferum Fr. Schmidt. were reported in this study. The chloroplast genomes were 152,837 bp for C. macrophyllum and 151,679 bp for C. flagelliferum.
Wen-Jie Yan   +5 more
doaj   +1 more source

The 2′-O-methylation status of a single guanosine controls transfer RNA–mediated Toll-like receptor 7 activation or inhibition

open access: yesJournal of Experimental Medicine, 2012
Bacterial transfer RNA can suppress the immunostimulatory activity of other bacterial tRNAs as a result of the presence of a guanosine modification.
Stefanie Jöckel   +10 more
semanticscholar   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Complete mitochondrial genome of the coconut black-headed caterpillar Opisina arenosella (Lepidoptera: Gelechioidea: Xyloryctidae)

open access: yesMitochondrial DNA. Part B. Resources, 2019
In the present study, we determined the complete mitogenome of Opisina arenosella, the first for the family Xyloryctidae. This mitochondrial genome contains 15,389 bp, with an A + T content of 80.5% and consists of 13 protein-coding genes, 22 transfer ...
Rui Meng, Yao He, Su Ao, Bo Cai
doaj   +1 more source

Transfer RNA methytransferases and their corresponding modifications in budding yeast and humans: activities, predications, and potential roles in human health.

open access: yesDNA and Cell Biology, 2012
Throughout the kingdoms of life, transfer RNA (tRNA) undergoes over 100 enzyme-catalyzed, methyl-based modifications. Although a majority of the methylations are conserved from bacteria to mammals, the functions of a number of these modifications are ...
William Towns, Thomas J. Begley
semanticscholar   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

Analysis of tRNA halves (tsRNAs) in serum from cattle challenged with bovine viral diarrhea virus

open access: yesGenetics and Molecular Biology
Acute infections of bovine viral diarrhea virus (BVDV) lead to a range of clinical presentations. Laboratory tests for detection depend on collection of samples during a short viremia. Acutely infected animals remain largely undiagnosed.
Tasia M. Taxis   +3 more
doaj   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Transfer RNA coded by the T4 bacteriophage genome. [PDF]

open access: green, 1968
S B Weiss   +3 more
openalex   +1 more source

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