Results 91 to 100 of about 929,368 (351)

Mapping Current Studies of tRNA Fragments onto Disease Landscape

Biomolecules
Transfer-RNA-derived fragments (tRFs) are a relatively recently discovered class of non-coding RNAs derived from both precursor and mature transfer RNAs (tRNAs).
Sathyanarayanan Vaidhyanathan, MacKenna Durbin, Adesupo A. Adetowubo, Lisa H. Do, Sheida Kavehmoghaddam, Sai Anusha Jonnalagadda, Bryan Ramirez Aguilar, Tamin Ortiz-Gomez, Yan X. Lin, Asim Dave, Fatmanur Kiliç, Alexa R. Karp, Mohammed Imthiyas Rahmah, Noor F. Riaz, Nikhila Mandava, Aleece Siner, Andrey Grigoriev   +16 more
doaj   +1 more source

The complete plastid genome of a marine microalgae Cryptophyceae sp. CCMP2293 (Cryptophyta)

Mitochondrial DNA. Part B. Resources, 2019
In this study, we present the complete plastid genome of Cryptophyceae sp. CCMP2293. The circular genome is 139,208 bp in length and contains 142 protein-coding genes (PCGs), 30 transfer RNA (tRNA) genes, 6 ribosome RNA (rRNA) genes, and 1 transfer ...
Kuipeng Xu, Shunxin Hu, Xianghai Tang
doaj   +1 more source

Retraction Note: Exosome-mediated transfer of lncRNA PART1 induces gefitinib resistance in esophageal squamous cell carcinoma via functioning as a competing endogenous RNA [PDF]

, 2023
Min Kang, Meiping Ren, Yan Li, Yuqiong Fu, Minmin Deng, Changping Li   +5 more
openalex   +1 more source

Role of the Mitochondrial Genome During Early Development in Mice [PDF]

, 1973
The role of the mitochondrial genome in early development and differentiation was studied in mouse embryos cultured in vitro from the two to four cell stage to the blastocyst (about 100 cells).
Chase, David G., Pikó, Lajos
core  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Idiosyncratic evolution of conserved eukaryote proteins that are similar in sequence to archaeal or bacterial proteins [PDF]

, 2008
Sequence comparisons have been made between the proteins of 571 prokaryote species including 46 archaea and 525 bacteria and the set of human proteins.
Roy J. Britten
core   +2 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Identification of novel clostridium perfringens type E strains that carry an iota toxin plasmid with a functional enterotoxin gene [PDF]

, 2011
Clostridium perfringens enterotoxin (CPE) is a major virulence factor for human gastrointestinal diseases, such as food poisoning and antibiotic associated diarrhea. The CPE-encoding gene (cpe) can be chromosomal or plasmid-borne.
A Deguchi, A Gurjar, A Heikinheimo, BA McClane, Bruce A. McClane, D Lepp, Herman Tse, HS Garmony, J Li, J Li, J Li, J Li, J Li, JA Parsons, Jihong Li, K Miyamoto, K Miyamoto, K Miyamoto, K Miyamoto, Kanako Mimura, Kazuaki Miyamoto, KH Harry, Masahiro Nagahama, MR Sarker, Natsuko Yumine, S Sayeed, S Sayeed, Shigeru Akimoto, SJ Billington, SR Mueller-Spits, T Hirokawa, Y Miki, Y Zhao   +32 more
core   +5 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Prebiotic chiral transfer from self-aminoacylating ribozymes may favor either handedness

Nature Communications
Modern life is essentially homochiral, containing D-sugars in nucleic acid backbones and L-amino acids in proteins. Since coded proteins are theorized to have developed from a prebiotic RNA World, the homochirality of L-amino acids observed in all known ...
Josh Kenchel, Alberto Vázquez-Salazar, Reno Wells, Krishna Brunton, Evan Janzen, Kyle M. Schultz, Ziwei Liu, Weiwei Li, Eric T. Parker, Jason P. Dworkin, Irene A. Chen   +10 more
doaj   +1 more source