Results 101 to 110 of about 868,050 (310)
Investigation into the relationship between ethylene and sulfur assimilation in Arabidopsis thaliana and onion (Allium cepa L.) : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science (with Honours) in Biochemistry at Massey University [PDF]
, 2006 The phytohormone ethylene (C2H4) mediates the adaptive responses of plants to various nutrient deficiencies including iron (Fe)-deficiency, phosphorus (P)-deficiency and potassium (K)-deficiency.
Sanggang, Fiona Ann
core
Molecular Oncology, EarlyView.Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi +12 more
wiley +1 more source
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
Molecular Oncology, EarlyView.In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza +3 more
wiley +1 more source
The Conformation of Transfer RNA
Kobunshi, 1972 一定の塩基配列で規定される転移リボ核酸(tRNA)は鎖内部での特異的塩基対形成によってクローバー葉形の二次構造をとる。三次元的にはクローバー葉構造が折りたたまれて高次構造を形成するが,その存在は主として熱変性過程の研究から明らかになった。t RNAのコンホメーションの安定化には陽イオン,とりわけ二価金属イオンが大きな効果を示す。Mg++,Mn++,Co++などはtRNAに約20～30個特異的に結合し,その会合定数は103～104の大きさである。ある種のtRNAには生物活性形と変性形が見出され,相互変換には二価イオンが決定的な役割を果す。活性形は約2～3個の二価イオン部位をよけいにもち,変換にはリン酸基の中和を伴うコンホメーション変化が起こると考えられる ...
openaire +3 more sources
Molecular Oncology, EarlyView.Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
RELEASE OF TRANSFER RNA DURING PEPTIDE CHAIN ELONGATION
, 1969 Jean Lucas‐Lenard, Anne‐Lise Haenni
openalex +1 more source
Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation
Molecular Oncology, EarlyView.Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza +5 more
wiley +1 more source